U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Name Type Language
SAPABLURSEN
USAN   INN  
Official Name English
ISIS 702843
Preferred Name English
sapablursen [INN]
Common Name English
DNA, D((2'-O-(2-METHOXYETHYL))M5RC-SP-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))RA-T-SP-T-SP-M5C-SP-M5C-SP-A-SP-A-SP-A-SP-G-SP-G-SP-G-SP-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))R
Systematic Name English
ISIS-702843
Code English
SAPABLURSEN [USAN]
Common Name English
IONIS TMPRSS6-LRX
Common Name English
Code System Code Type Description
NCI_THESAURUS
C179118
Created by admin on Wed Apr 02 08:03:51 GMT 2025 , Edited by admin on Wed Apr 02 08:03:51 GMT 2025
PRIMARY
FDA UNII
DXS4HJC32N
Created by admin on Wed Apr 02 08:03:51 GMT 2025 , Edited by admin on Wed Apr 02 08:03:51 GMT 2025
PRIMARY
SMS_ID
300000001161
Created by admin on Wed Apr 02 08:03:51 GMT 2025 , Edited by admin on Wed Apr 02 08:03:51 GMT 2025
PRIMARY
CAS
2273007-95-5
Created by admin on Wed Apr 02 08:03:51 GMT 2025 , Edited by admin on Wed Apr 02 08:03:51 GMT 2025
PRIMARY
USAN
HI-06
Created by admin on Wed Apr 02 08:03:51 GMT 2025 , Edited by admin on Wed Apr 02 08:03:51 GMT 2025
PRIMARY
INN
11518
Created by admin on Wed Apr 02 08:03:51 GMT 2025 , Edited by admin on Wed Apr 02 08:03:51 GMT 2025
PRIMARY INN
Sugar Site Range Site Count
Deoxyribose (DNA) 1_6-1_15 10 / 20
2'-O-Methoxyethyl ribose 1_1-1_5;1_16-1_20 10 / 20
Linkage Site Range Site Count
Phosporothioate 1_2;1_7-1_16;1_20 12 / 19
Phosphate 1_3-1_6;1_17-1_19 7 / 19
ACTIVE MOIETY
SAPABLURSEN
SALT/SOLVATE (PARENT)
SAPABLURSEN SODIUM
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966