MRTX-1133

Details

Stereochemistry	MIXED
Molecular Formula	C33H31F3N6O2
Molecular Weight	600.6334
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=CC2=CC=C(F)C(C#C)=C2C(=C1)C3=C(F)C4=C(C=N3)C(=NC(OC[C@@]56CCCN5C[C@H](F)C6)=N4)N7CC8CCC(C7)N8

InChI

InChIKey=SCLLZBIBSFTLIN-IFMUVJFISA-N

InChI=1S/C33H31F3N6O2/c1-2-23-26(35)7-4-18-10-22(43)11-24(27(18)23)29-28(36)30-25(13-37-29)31(41-15-20-5-6-21(16-41)38-20)40-32(39-30)44-17-33-8-3-9-42(33)14-19(34)12-33/h1,4,7,10-11,13,19-21,38,43H,3,5-6,8-9,12,14-17H2/t19-,20?,21?,33+/m1/s1

HIDE SMILES / InChI

Approval Year

Name

Type

Language

MRTX-1133

Code

English

MRTX1133

Preferred Name

English

2-Naphthalenol, 4-[4-(3,8-diazabicyclo[3.2.1]oct-3-yl)-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]pyrido[4,3-d]pyrimidin-7-yl]-5-ethynyl-6-fluoro-

Systematic Name

English

4-[4-(3,8-Diazabicyclo[3.2.1]oct-3-yl)-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]pyrido[4,3-d]pyrimidin-7-yl]-5-ethynyl-6-fluoro-2-naphthalenol

Systematic Name

English

Code System Code Type Description

NCI_THESAURUS

C200319

Created by admin on Wed Apr 02 16:18:32 GMT 2025 , Edited by admin on Wed Apr 02 16:18:32 GMT 2025

PRIMARY

CAS

2621928-55-8

Created by admin on Wed Apr 02 16:18:32 GMT 2025 , Edited by admin on Wed Apr 02 16:18:32 GMT 2025

PRIMARY

PUBCHEM

156124857

Created by admin on Wed Apr 02 16:18:32 GMT 2025 , Edited by admin on Wed Apr 02 16:18:32 GMT 2025

PRIMARY

FDA UNII

DU32DM9CHD

Created by admin on Wed Apr 02 16:18:32 GMT 2025 , Edited by admin on Wed Apr 02 16:18:32 GMT 2025

PRIMARY

ACTIVE MOIETY


					DU32DM9CHD

MRTX-1133