| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H4N2O4 |
| Molecular Weight | 168.107 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[O-][N+](=O)C1=CC(=CC=C1)[N+]([O-])=O
InChI
InChIKey=WDCYWAQPCXBPJA-UHFFFAOYSA-N
InChI=1S/C6H4N2O4/c9-7(10)5-2-1-3-6(4-5)8(11)12/h1-4H
m-Dinitrobenzene (1,3-DBN) is a synthetic compound used in manufacture of explosives. 1,3-DNB has been used as a camphor substitute in nitrocellulose, a compound used in explosives and propellants.1,3-DNB was manufactured during both world wars as a component in the explosive roburite. Commercially, 1,3-DNB has been used extensively as an organic intermediate for m-phenylenediamine, a chemical used in the synthesis of aramid fibers and spandex. 1,3-DNB is an industrial chemical used in organic synthesis and dyes. In medicine, 1,3-DNB was used for colorimetric determination of 17-ketosteroids.
CNS Activity
Originator
Approval Year
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
PubMed
Sample Use Guides
In, animals, 1,3-DNB is rapidly absorbed by the oral route; data from one study indicate that at least 70% of a single oral dose was absorbed. In animals, depending on the vehicle, 1,3-DNB can also be readily absorbed through the skin.
Route of Administration:
Other
For colorimetric determination of 17-ketosteroids, into the calorimeter tube were accurately measured 0.2 cc. of a test solution, 0.2 cc. of m-dinitrobenzene solution, and 0.2 cc. of KOH solution. The tubes were then corked, gently shaken, and placed in a water bath for 45 minutes at 25°. At the end of 45 minutes the solution was diluted with 10.0 cc. of redistilled 95 per cent EtOH from a 10 cc. Koch burette. After the outside of the tube was dried and polished, it was placed in a rack for 3 minutes and read in the photoelectric calorimeter previously adjusted to 100 by means of the resistances with the blank in place.
SUBSTANCE RECORD
