NORFLURANE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C2H2F4
Molecular Weight	102.0309
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

FCC(F)(F)F

InChI

InChIKey=LVGUZGTVOIAKKC-UHFFFAOYSA-N

InChI=1S/C2H2F4/c3-1-2(4,5)6/h1H2

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/27393489 | https://www.ncbi.nlm.nih.gov/pubmed/24565651 | https://www.drugbank.ca/drugs/DB13116 |

Norflurane (1,1,1,2-Tetrafluoroethane) is a non-flammable gas used primarily as a "high-temperature" refrigerant for domestic refrigeration and automobile air conditioners. Other uses include plastic foam blowing, as a cleaning solvent, a propellant for the delivery of pharmaceuticals (e.g. bronchodilators), wine cork removers, gas dusters, and in air driers for removing the moisture from compressed air. Liquid Norflurane absorbs a high amount of thermal energy from the environment during its evaporation at atmospheric pressure. Norflurane is commercially available as a liquid in pressurized cylinders or cans. Norflurane is used as a propellant for some metered dose inhalers and as an inhalational anesthetic agent in animal studies.

Approval Year

PubMed

Title	Date	PubMed
Characterisation of the aggregation behaviour in a salmeterol and fluticasone propionate inhalation aerosol system.	2001 Jun 19	11397578
CH-stretching overtone spectroscopy of 1,1,1,2-tetrafluoroethane.	2005 Jun 23	16839056
Probing the internal competition between alpha- and beta-elimination by fluorine substitution in adsorbed ethyl groups on Cu(100).	2005 Nov 24	16853787
Toxicokinetics of 1,1,1,2-tetrafluoroethane (HFC-134a) in male volunteers after experimental exposure.	2006 Nov 1	17030466
Extrinsic allergic alveolitis with eosinophil infiltration induced by 1,1,1,2-tetrafluoroethane (HFC-134a): a case report.	2007	17827848
One-solvent extraction of astaxanthin from lactic acid fermented shrimp wastes.	2007 Dec 12	18020413
Determination of reference ultrasound parameters for model and hydrofluoroalkane propellants using high-resolution ultrasonic spectroscopy.	2008	18459053
Effect of topical aerosol skin refrigerant (spray and stretch technique) on passive and active stretching.	2008 Apr	19083662
Decomposition of hydrofluorocarbons in a dielectric-packed plasma reactor.	2008 Jul 24	18582026
Estimated 2017 refrigerant emissions of 2,3,3,3-tetrafluoropropene (HFC-1234yf) in the United States resulting from automobile air conditioning.	2009 Dec 15	20000517
The involvement of the transient receptor potential A1 (TRPA1) in the maintenance of mechanical and cold hyperalgesia in persistent inflammation.	2010 Mar	20056530
Symmetry measures of the electron density.	2010 Oct	20652983
Microscopic structure of liquid 1-1-1-2-tetrafluoroethane (R134a) from Monte Carlo simulation.	2010 Oct 28	20830386

Patents

Name

Type

Language

NORFLURANE

Official Name

English

HFA-134A PROPELLANT

Code

English

Norflurane [WHO-DD]

Common Name

English

SOLKANE 134A

Brand Name

English

HYDROFLUOROCARBON 134A

Official Name

English

GENETRON 134A

Common Name

English

FORANE 134A

Brand Name

English

1,1,1,2-Tetrafluoroethane

Systematic Name

English

norflurane [INN]

Common Name

English

NORFLURANE [HSDB]

Common Name

English

NORFLURANE [MART.]

Common Name

English

FREON 134A

Common Name

English

HFA 134A

Code

English

R-134A

Code

English

DYMEL 134A

Brand Name

English

NORFLURANE [EP MONOGRAPH]

Common Name

English

HFA-134-A

Code

English

HYDROFLUOROCARBON 134A [INCI]

Common Name

English

SUVA 134A

Common Name

English

HFC-134A [MI]

Common Name

English

NORFLURANE [USAN]

Common Name

English

HFA-134A

Common Name

English

NORFLURANE [II]

Common Name

English

HFC-134A

Code

English

TETRAFLUOROETHANE [VANDF]

Common Name

English

ETHANE, 1,1,1,2-TETRAFLUORO-

Systematic Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

100895