Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C21H22N4O3 |
| Molecular Weight | 378.4244 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCOC1=NC=C(C)C2=C1[C@H](C3=CC=C(C=C3OC)C#N)C(C(N)=O)=C(C)N2
InChI
InChIKey=BTBHLEZXCOBLCY-QGZVFWFLSA-N
InChI=1S/C21H22N4O3/c1-5-28-21-18-17(14-7-6-13(9-22)8-15(14)27-4)16(20(23)26)12(3)25-19(18)11(2)10-24-21/h6-8,10,17,25H,5H2,1-4H3,(H2,23,26)/t17-/m1/s1
FINERENONE is a potent and selective nonsteroidal mineralocorticoid receptor antagonist. Results in preclinical studies showed that lower doses of FINERENONE were needed to achieve similar cardiorenal protective effects compared to both spironolactone and eplerenone. It is in phase III clinical trials for the treatment of diabetic kidney disease.
Approval Year
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DTXSID10146928
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BC-45
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C169981
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1050477-31-0
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Finerenone
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CHEMBL2181927
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100000169992
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9634
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60150535
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DE2O63YV8R
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SUB183743
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2562811
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DE2O63YV8R
Created by
admin on Sat Dec 16 05:41:51 GMT 2023 , Edited by admin on Sat Dec 16 05:41:51 GMT 2023
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ACTIVE MOIETY
