MAK-683 HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H17FN6O.ClH
Molecular Weight	412.848
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CC1=NC=CC=C1C2=CN=C(NCC3=C4CCOC4=CC=C3F)N5C=NN=C25

InChI

InChIKey=YHAMPXCHEHVBSA-UHFFFAOYSA-N

InChI=1S/C20H17FN6O.ClH/c1-12-13(3-2-7-22-12)16-10-24-20(27-11-25-26-19(16)27)23-9-15-14-6-8-28-18(14)5-4-17(15)21;/h2-5,7,10-11H,6,8-9H2,1H3,(H,23,24);1H

HIDE SMILES / InChI

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Polycomb protein EED 2 Target ID: O75530 Gene ID: 8726.0 Gene Symbol: EED Target Organism: Homo sapiens (Human) Sources: https://www.cancer.gov/publications/dictionaries/cancer-drug/def/eed-inhibitor-mak683 \| https://patents.google.com/patent/US20160176882A1/en	Inhibitor 8504

Patents

Name

Type

Language

1,2,4-TRIAZOLO(4,3-C)PYRIMIDIN-5-AMINE, N-((5-FLUORO-2,3-DIHYDRO-4-BENZOFURANYL)METHYL)-8-(2-METHYL-3-PYRIDINYL)-, HYDROCHLORIDE (1:1)

Preferred Name

English

MAK-683 HYDROCHLORIDE

Common Name

English

Code System Code Type Description

CAS

2170606-94-5

Created by admin on Tue Apr 01 18:54:46 GMT 2025 , Edited by admin on Tue Apr 01 18:54:46 GMT 2025

PRIMARY

FDA UNII

D552T2P76M

Created by admin on Tue Apr 01 18:54:46 GMT 2025 , Edited by admin on Tue Apr 01 18:54:46 GMT 2025

PRIMARY

PUBCHEM

138734886

Created by admin on Tue Apr 01 18:54:46 GMT 2025 , Edited by admin on Tue Apr 01 18:54:46 GMT 2025

PRIMARY

ACTIVE MOIETY


					4K446Z8N51

MAK-683

SUBSTANCE RECORD


					D552T2P76M

MAK-683 HYDROCHLORIDE