U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C26H30O6
Molecular Weight 438.5128
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 3,6-DIMETHYLMANGOSTIN

SMILES

COC1=CC2=C(C(=O)C3=C(O)C(CC=C(C)C)=C(OC)C=C3O2)C(CC=C(C)C)=C1OC

InChI

InChIKey=FCIKYGUVHWZSJV-UHFFFAOYSA-N
InChI=1S/C26H30O6/c1-14(2)8-10-16-18(29-5)12-20-23(24(16)27)25(28)22-17(11-9-15(3)4)26(31-7)21(30-6)13-19(22)32-20/h8-9,12-13,27H,10-11H2,1-7H3

HIDE SMILES / InChI
3,6-DIMETHYLMANGOSTIN (Fuscaxanthone C) is a constituent of Garcinia mangostana (mangosteen). Fuscaxanthone C has shown α-glucosidase inhibitory activity.

Originator

Curator's Comment: Ito C. et al. from Meijo University, Japan

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Chemical constituents of Garcinia fusca: structure elucidation of eight new xanthones and their cancer chemopreventive activity.
2003 Feb
Cytotoxic constituents from Cratoxylum arborescens.
2005 Feb
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
Fuscaxanthone C showed 53.8% inhibition of α-glucosidase activity at a concentration of 100 uM.
Name Type Language
3,6-DIMETHYLMANGOSTIN
MI  
Common Name English
MANGOSTIN, DIMETHYL-
Common Name English
XANTHEN-9-ONE, 1-HYDROXY-3,6,7-TRIMETHOXY-2,8-BIS(3-METHYL-2-BUTENYL)-
Systematic Name English
1-HYDROXY-3,6,7-TRIMETHOXY-2,8-BIS-(3-METHYL-2-BUTEN-1-YL)-9H-XANTHEN-9-ONE
Systematic Name English
FUSCAXANTHONE C
Brand Name English
9H-XANTHEN-9-ONE, 1-HYDROXY-3,6,7-TRIMETHOXY-2,8-BIS(3-METHYL-2-BUTEN-1-YL)-
Systematic Name English
NSC-27594
Code English
3,6-DIMETHYLMANGOSTIN [MI]
Common Name English
Code System Code Type Description
PUBCHEM
231412
Created by admin on Sat Dec 16 03:05:56 GMT 2023 , Edited by admin on Sat Dec 16 03:05:56 GMT 2023
PRIMARY
NSC
27594
Created by admin on Sat Dec 16 03:05:56 GMT 2023 , Edited by admin on Sat Dec 16 03:05:56 GMT 2023
PRIMARY
FDA UNII
D047BK20VG
Created by admin on Sat Dec 16 03:05:56 GMT 2023 , Edited by admin on Sat Dec 16 03:05:56 GMT 2023
PRIMARY
EPA CompTox
DTXSID80165525
Created by admin on Sat Dec 16 03:05:56 GMT 2023 , Edited by admin on Sat Dec 16 03:05:56 GMT 2023
PRIMARY
CAS
15404-76-9
Created by admin on Sat Dec 16 03:05:56 GMT 2023 , Edited by admin on Sat Dec 16 03:05:56 GMT 2023
PRIMARY