HEXAHYDROAZEPINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H13N
Molecular Weight	99.1741
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C1CCCNCC1

InChI

InChIKey=ZSIQJIWKELUFRJ-UHFFFAOYSA-N

InChI=1S/C6H13N/c1-2-4-6-7-5-3-1/h7H,1-6H2

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Total synthesis of (-)-stemospironine.	2001 Aug 23	11506618
Synthesis of DTPA analogues derived from piperidine and azepane: potential contrast enhancement agents for magnetic resonance imaging.	2001 Nov 16	11701031
Quantitative structure-activity relationships for a series of symmetrical bisquaternary anticancer compounds.	2002 Jul	11983519
Nicotinic acetylcholine receptor binding of imidacloprid-related diaza compounds with various ring sizes and their insecticidal activity against Musca domestica.	2002 May	11997976
Heterocyclic rimantadine analogues with antiviral activity.	2003 Dec 1	14642592
Asymmetric cyclization via memory of chirality: a concise access to cyclic amino acids with a quaternary stereocenter.	2003 Oct 29	14570459
Total synthesis of (-)-stemonine.	2003 Sep 4	12943427
A general route to the synthesis of 1,5-methano- and 1,5-ethano- 2,3,4,5-tetrahydro-1H-3-benzazepines.	2004 Aug 20	15307752
Design, synthesis, and evaluation of metabolism-based analogues of haloperidol incapable of forming MPP+-like species.	2004 Jan 29	14736232
Asymmetric dihydroxylation of d-glucose derived alpha,beta-unsaturated ester: synthesis of azepane and nojirimycin analogues.	2004 Jul 9	15230599
Structure-based optimization of novel azepane derivatives as PKB inhibitors.	2004 Mar 11	14998327
Interactions of novel morpholine and hexamethylene derivatives of anthracycline antibiotics with DNA.	2004 Sep-Oct	15540609
A deoxynucleotide derivatization methodology for improving LC-ESI-MS detection.	2005 Apr 15	15828769
Sequence specificity of formaldehyde-mediated covalent binding of anthracycline derivatives to DNA.	2005 Jan 1	15588709
Cytotoxicity, cellular uptake and DNA damage by daunorubicin and its new analogues with modified daunosamine moiety.	2005 May-Jul	16328893
Effects of anthracycline derivatives on human leukemia K562 cell growth and differentiation.	2005 Nov 15	16185667
Synthesis and antimelanoma activity of reversed amide analogues of N-acetyl-4-S-cysteaminylphenol.	2006	16898270
Hydrogen-bonding patterns in enaminones: (2Z)-1-(4-bromophenyl)-2-(pyrrolidin-2-ylidene)ethanone and its piperidin-2-ylidene and azepan-2-ylidene analogues.	2007 Dec	18057627
Synthesis of densely functionalized enantiopure indolizidines by ring-closing metathesis (RCM) of hydroxylamines from carbohydrate-derived nitrones.	2007 Dec 12	18076753
DFT and ab initio calculations of the vibrational frequencies and visible spectra of triazenes derived from cyclic amines.	2007 Jun	16965932
[How thione phosphonates inhibit activities of various cholinesterases].	2007 Mar-Apr	17674706
Stereoselective synthesis of 2-dienyl-substituted piperidines using an eta4-dienetricarbonyliron complex as the stereocontrolling element in a double reductive amination cascade.	2007 Oct 21	17912386
Total synthesis of (-)-balanol, all stereoisomers, their N-tosyl analogues, and fully protected ophiocordin: an easy route to hexahydroazepine cores from garner aldehydes.	2008	18399526
New insights into a bacterial metabolic and detoxifying association responsible for the mineralization of the thiocarbamate herbicide molinate.	2008 Apr	18375797
Synthesis of MCM-22 zeolite by an ultrasonic-assisted aging procedure.	2008 Apr	17845863
(3S,4S)-3-Ethyl-4-hydr-oxy-3-(3-methoxy-phen-yl)-1-methyl-azepan-1-ium d-tartrate dihydrate.	2008 Apr 2	21202277
Bazedoxifene for the prevention of postmenopausal osteoporosis.	2008 Dec	19337430
Molecular dynamics simulations of the amyloid-beta binding alcohol dehydrogenase (ABAD) enzyme.	2008 Nov 1	18835182
Azetidine, pyrrolidine and hexamethyleneimine at 170 K.	2008 Oct	18838771
1-Methyl-3-(3-oxocyclo-hex-1-en-yl)azepan-2-one.	2008 Sep 13	21201143
Cytotoxicity and inhibitory properties against topoisomerase II of doxorubicin and its formamidine derivatives.	2009	19238256
Cytotoxicity and cellular uptake of doxorubicin and its formamidine derivatives in HL60 sensitive and HL60/MX2 resistant cells.	2009 Apr	19414398
Aminoglycosides: molecular insights on the recognition of RNA and aminoglycoside mimics.	2009 Apr 28	19812740
The discovery of azepane sulfonamides as potent 11beta-HSD1 inhibitors.	2009 Aug 15	19625185
Novel mannosidase inhibitors probe glycoprotein degradation pathways in cells.	2009 Dec	19234785
In vitro and in vivo antitumor activity of platinum(II) complexes with thiosemicarbazones derived from 2-formyl and 2-acetyl pyridine and containing ring incorporated at N(4)-position: synthesis, spectroscopic study and crystal structure of platinum(II) complexes with thiosemicarbazones, potential anticancer agents.	2009 Mar	18848372
(3S,4R)-3-Ethyl-4-hydr-oxy-3-(3-methoxy-phen-yl)-1-methyl-azepanium (2R,3R)-2,3-bis-(benzo-yloxy)-3-carboxy-propionate.	2010 Apr 17	21579145
Polymer resins for recovery of valuable metals.	2010 Aug	20387092
Identification of N-(2-(azepan-1-yl)-2-phenylethyl)-benzenesulfonamides as novel inhibitors of GlyT1.	2010 Aug 15	20637614
3-[(3S)-3-Ethyl-1-methyl-azepan-3-yl]phenyl N-(4-fluoro-phen-yl)carbamate.	2010 Jun 26	21588029
Discovery of 4-amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides as selective, orally active inhibitors of protein kinase B (Akt).	2010 Mar 11	20151677
An overview of recent development in composite catalysts from porous materials for various reactions and processes.	2010 May 18	20559508

Patents

Name

Type

Language

HEXAHYDROAZEPINE

Systematic Name

English

HOMOPIPERIDINE

Systematic Name

English

HEXAMETHYLENIMINE

Common Name

English

PERHYDROAZEPINE

Systematic Name

English

1-AZACYCLOHEPTANE

Systematic Name

English

HEXAMETHYLENEIMINE

Common Name

English

HEXAMETHYLENEIMINE [HSDB]

Common Name

English

CYCLOHEXAMETHYLENIMINE

Common Name

English

NSC-16236

Code

English

1H-AZEPINE, HEXAHYDRO-

Systematic Name

English

Code System Code Type Description

WIKIPEDIA

Azepane