U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C32H39N7O4S
Molecular Weight 617.762
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Vanzacaftor

SMILES

CC1(C)C[C@H]2CN1C3=NC(=CC=C3C(=O)NS(=O)(=O)C4=CC=CC(NCCC2)=N4)N5C=CC(OCCC6C7(CC7)C68CC8)=N5

InChI

InChIKey=VCSUIBJKYCVWNF-NRFANRHFSA-N
InChI=1S/C32H39N7O4S/c1-30(2)19-21-5-4-16-33-24-6-3-7-27(34-24)44(41,42)37-29(40)22-8-9-25(35-28(22)38(30)20-21)39-17-10-26(36-39)43-18-11-23-31(12-13-31)32(23)14-15-32/h3,6-10,17,21,23H,4-5,11-16,18-20H2,1-2H3,(H,33,34)(H,37,40)/t21-/m0/s1

HIDE SMILES / InChI

Approval Year

Name Type Language
Vanzacaftor
INN   USAN  
Official Name English
VX-121
Code English
vanzacaftor [INN]
Common Name English
VANZACAFTOR [USAN]
Common Name English
13H-17,20-Methano-8,12-nitrilo-12H-pyrido[3,2-d][1,2,6,13]thiatriazacyclooctadecin-5(6H)-one, 2-[3-(2-dispiro[2.0.2.1]hept-7-ylethoxy)-1H-pyrazol-1-yl]-14,15,16,17,18,19-hexahydro-19,19-dimethyl-, 7,7-dioxide, (17S)-
Systematic Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 777220
Created by admin on Sat Dec 16 15:08:57 GMT 2023 , Edited by admin on Sat Dec 16 15:08:57 GMT 2023
Code System Code Type Description
SMS_ID
300000046984
Created by admin on Sat Dec 16 15:08:57 GMT 2023 , Edited by admin on Sat Dec 16 15:08:57 GMT 2023
PRIMARY
USAN
LM-135
Created by admin on Sat Dec 16 15:08:57 GMT 2023 , Edited by admin on Sat Dec 16 15:08:57 GMT 2023
PRIMARY
CAS
2374124-49-7
Created by admin on Sat Dec 16 15:08:57 GMT 2023 , Edited by admin on Sat Dec 16 15:08:57 GMT 2023
PRIMARY
PUBCHEM
139399801
Created by admin on Sat Dec 16 15:08:57 GMT 2023 , Edited by admin on Sat Dec 16 15:08:57 GMT 2023
PRIMARY
INN
11971
Created by admin on Sat Dec 16 15:08:57 GMT 2023 , Edited by admin on Sat Dec 16 15:08:57 GMT 2023
PRIMARY
NCI_THESAURUS
C188560
Created by admin on Sat Dec 16 15:08:57 GMT 2023 , Edited by admin on Sat Dec 16 15:08:57 GMT 2023
PRIMARY
FDA UNII
COM1POP492
Created by admin on Sat Dec 16 15:08:57 GMT 2023 , Edited by admin on Sat Dec 16 15:08:57 GMT 2023
PRIMARY