Details
Stereochemistry | ACHIRAL |
Molecular Formula | C10H8O5 |
Molecular Weight | 208.1675 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=C(O)C(O)=C2OC(=O)C=CC2=C1
InChI
InChIKey=HAVWRBANWNTOJX-UHFFFAOYSA-N
InChI=1S/C10H8O5/c1-14-6-4-5-2-3-7(11)15-10(5)9(13)8(6)12/h2-4,12-13H,1H3
Approval Year
PubMed
Title | Date | PubMed |
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Antioxidant activity of Fraxetin: in vivo and ex vivo parameters in normal situation versus induced stress. | 2001 Jul |
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Mono- and dinuclear ruthenium carbonyl complexes with redox-active dioxolene ligands: electrochemical and spectroscopic studies and the properties of the mixed-valence complexes. | 2003 Dec 1 |
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Suppression of lipid hydroperoxide-induced oxidative damage to cellular DNA by esculetin. | 2003 Jun |
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Neuroprotective effect of fraxetin and myricetin against rotenone-induced apoptosis in neuroblastoma cells. | 2004 May 29 |
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Isolation and purification of coumarin compounds from Cortex fraxinus by high-speed counter-current chromatography. | 2005 Apr 29 |
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Bone morphogenetic protein-2 and -4 (BMP-2 and -4) mediates fraxetin-induced maturation and differentiation in human osteoblast-like cell lines. | 2006 Jan |
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Fraxetin inhibits the induction of anti-Fas IgM, tumor necrosis factor-alpha and interleukin-1beta-mediated apoptosis by Fas pathway inhibition in human osteoblastic cell line MG-63. | 2006 Jul |
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Metabolic fate of fraxin administered orally to rats. | 2006 May |
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A new C9 nor-isoprenoid glucoside from Rantherium suaveolens. | 2007 Aug |
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[Studies on chemical constituents of Sarcandra glabra]. | 2008 Apr |
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[Studies on chemical constituents from stem barks of Fraxinus paxiana]. | 2008 Aug |
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An in vitro screening cascade to identify neuroprotective antioxidants in ALS. | 2009 Apr 15 |
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Dual anti-oxidative effects of fraxetin isolated from Fraxinus rhinchophylla. | 2009 Sep |
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Inhibitory effects of coumarins from the stem barks of Fraxinus rhynchophylla on adipocyte differentiation in 3T3-L1 cells. | 2010 |
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Curcumin reduces alpha-synuclein induced cytotoxicity in Parkinson's disease cell model. | 2010 Apr 30 |
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Antioxidant activities of coumarins from Korean medicinal plants and their structure-activity relationships. | 2010 Jan |
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Code System | Code | Type | Description | ||
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C105671
Created by
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5273569
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574-84-5
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DTXSID00205992
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5169
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CD3GD44O3K
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209-376-2
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m5564
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admin on Fri Dec 15 18:36:10 GMT 2023 , Edited by admin on Fri Dec 15 18:36:10 GMT 2023
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Fraxetin
Created by
admin on Fri Dec 15 18:36:10 GMT 2023 , Edited by admin on Fri Dec 15 18:36:10 GMT 2023
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SUBSTANCE RECORD