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Details

Stereochemistry ACHIRAL
Molecular Formula C6H10N6
Molecular Weight 166.1838
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CYROMAZINE

SMILES

NC1=NC(NC2CC2)=NC(N)=N1

InChI

InChIKey=LVQDKIWDGQRHTE-UHFFFAOYSA-N
InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)

HIDE SMILES / InChI

Description

Cyromazine, an insect growth regulator, affects larval and pupal cuticles in dipterans and some other insects. The mode of action of this aminotriazine is not known yet, though it has been shown not to inhibit the synthesis of chitin and cuticular proteins. Cyromazine may, however, act on some step(s) of sclerotization of the cuticle. Cyromazine is not a cholinesterase inhibitor. As an insect growth regulator, cyrozine exerts its toxic action by affecting the nervous system of the immature stages (larvae) of certain insects.

CNS Activity

Originator

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
Cyromazine Spray-On

PubMed

Sample Use Guides

In Vivo Use Guide
In a series of 4 trials, dairy calves housed in outdoor hutches were administered technical cyromazine daily at rates of 0, 0.1, 0.5, and 1.0 mg/kg body weight.
Route of Administration: Oral
In Vitro Use Guide
There was no significant inhibition of dihydrofolate reductase (DHFR) from larvae of the blowfly, Protophormia terraenovae, and from hen liver at 100 uM by cyromazine.