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Details

Stereochemistry ACHIRAL
Molecular Formula C15H21N3OS.ClH
Molecular Weight 327.873
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ZOLAMINE HYDROCHLORIDE

SMILES

Cl.COC1=CC=C(CN(CCN(C)C)C2=NC=CS2)C=C1

InChI

InChIKey=GSDXPNOJFAITBE-UHFFFAOYSA-N
InChI=1S/C15H21N3OS.ClH/c1-17(2)9-10-18(15-16-8-11-20-15)12-13-4-6-14(19-3)7-5-13;/h4-8,11H,9-10,12H2,1-3H3;1H

HIDE SMILES / InChI

Description

Zolamine is an antihistamine with local anesthetic properties. Zolamine is reported to have a low incidence of side effects and is used clinically both as an antihistaminic and a topical local anesthetic.

Approval Year

1951
104
Sourcing

Sourcing

Vendor/AggregatorIDURL
ABI Chem
AC1L23QG
Compound Cloud
14386
Compound Cloud
14387
HongKong Chemhere
SCE20783
MuseChem
M049385
ZINC
ZINC000000002257
http://zinc15.docking.org/substances/ZINC000000002257
PubMed

PubMed

TitleDatePubMed
Patents

Patents

US20060110428A1
11
WO2003030818A2
4

Sample Use Guides

In Vivo Use Guide
Eight female pigs were anaesthetized byinitially intramuscular injection of a 1 ml mixture con-sisting of zolamine 5 mg/ml, butorphanol 1 mg/ml,ketamine 10 mg/ml and xylazin 2 mg/ml, followedby continuous intravenous infusion of propofol10 mg/kg per hour and fentanyl 0.025 mg/kg perhour throughout the operation.
Route of Administration: Intramuscular
Name Type Language
ZOLAMINE HYDROCHLORIDE
MI   USAN  
USAN  
Official Name English
WL-291
Code English
ZOLAMINE HYDROCHLORIDE [MI]
Common Name English
ZOLAMINE HYDROCHLORIDE [USAN]
Common Name English
WL 291
Code English
2-((2-(DIMETHYLAMINO)ETHYL)-(P-METHOXYBENZYL)AMINO)THIAZOLE MONOHYDROCHLORIDE
Common Name English
N,N-DIMETHYL-N'-2-THIAZOLYL-N'-P-METHOXYBENZYL-ETHYL-ENEDIAMINE HYDROCHLORIDE
Common Name English
1,2-ETHANEDIAMINE, N-((4-METHOXYPHENYL)METHYL)-N',N'-DIMETHYL-N-2-THIAZOLYL-, MONOHYDROCHLORIDE
Common Name English
194-B
Code English
ZOLAMINE HCL
Common Name English
Classification Tree Code System Code
CFR 21 CFR 310.201
Created by admin on Fri Dec 15 15:05:25 GMT 2023 , Edited by admin on Fri Dec 15 15:05:25 GMT 2023
NCI_THESAURUS C29578
Created by admin on Fri Dec 15 15:05:25 GMT 2023 , Edited by admin on Fri Dec 15 15:05:25 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C81149
Created by admin on Fri Dec 15 15:05:25 GMT 2023 , Edited by admin on Fri Dec 15 15:05:25 GMT 2023
PRIMARY
MERCK INDEX
m539
Created by admin on Fri Dec 15 15:05:25 GMT 2023 , Edited by admin on Fri Dec 15 15:05:25 GMT 2023
PRIMARY Merck Index
PUBCHEM
14386
Created by admin on Fri Dec 15 15:05:25 GMT 2023 , Edited by admin on Fri Dec 15 15:05:25 GMT 2023
PRIMARY
CAS
1155-03-9
Created by admin on Fri Dec 15 15:05:25 GMT 2023 , Edited by admin on Fri Dec 15 15:05:25 GMT 2023
PRIMARY
FDA UNII
C2B9CF1640
Created by admin on Fri Dec 15 15:05:25 GMT 2023 , Edited by admin on Fri Dec 15 15:05:25 GMT 2023
PRIMARY
ChEMBL
CHEMBL127453
Created by admin on Fri Dec 15 15:05:25 GMT 2023 , Edited by admin on Fri Dec 15 15:05:25 GMT 2023
PRIMARY
EPA CompTox
DTXSID70151119
Created by admin on Fri Dec 15 15:05:25 GMT 2023 , Edited by admin on Fri Dec 15 15:05:25 GMT 2023
PRIMARY
ACTIVE MOIETY
Structure of ZOLAMINE
NIH
NCATS
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