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Details

Stereochemistry RACEMIC
Molecular Formula C22H35NO5
Molecular Weight 393.517
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIVABUTEROL

SMILES

CC(C)(C)NCC(O)C1=CC(OC(=O)C(C)(C)C)=CC(OC(=O)C(C)(C)C)=C1

InChI

InChIKey=VJJOKWOJJZKXNV-UHFFFAOYSA-N
InChI=1S/C22H35NO5/c1-20(2,3)18(25)27-15-10-14(17(24)13-23-22(7,8)9)11-16(12-15)28-19(26)21(4,5)6/h10-12,17,23-24H,13H2,1-9H3

HIDE SMILES / InChI
Divabuterol or terbutaline dipivalate is a prodrug of terbutaline. The half-life of terbutaline dipivalate in human plasma is less than five minutes. Therapeutically, most forms of terbutaline can be used as bronchodilators in antiasthmatic treatment, as smooth muscle relaxants to treat premature labour (uterine relaxant) and for a number of other indications.

Approval Year

PubMed

PubMed

TitleDatePubMed
New lipophilic terbutaline ester prodrugs with long effect duration.
1984 Jan
Patents

Patents

Name Type Language
DIVABUTEROL
INN  
INN  
Official Name English
divabuterol [INN]
Common Name English
(±)-5-(2-(TERT-BUTYLAMINO)-1-HYDROXYETHYL)-M-PHENYLENE DIPIVALATE
Systematic Name English
KWD-2085
Code English
Classification Tree Code System Code
NCI_THESAURUS C319
Created by admin on Fri Dec 15 16:21:14 GMT 2023 , Edited by admin on Fri Dec 15 16:21:14 GMT 2023
Code System Code Type Description
EVMPD
SUB06337MIG
Created by admin on Fri Dec 15 16:21:14 GMT 2023 , Edited by admin on Fri Dec 15 16:21:14 GMT 2023
PRIMARY
INN
5489
Created by admin on Fri Dec 15 16:21:14 GMT 2023 , Edited by admin on Fri Dec 15 16:21:14 GMT 2023
PRIMARY
ChEMBL
CHEMBL2107638
Created by admin on Fri Dec 15 16:21:14 GMT 2023 , Edited by admin on Fri Dec 15 16:21:14 GMT 2023
PRIMARY
FDA UNII
BVG9H4U2ZB
Created by admin on Fri Dec 15 16:21:14 GMT 2023 , Edited by admin on Fri Dec 15 16:21:14 GMT 2023
PRIMARY
CAS
54592-27-7
Created by admin on Fri Dec 15 16:21:14 GMT 2023 , Edited by admin on Fri Dec 15 16:21:14 GMT 2023
PRIMARY
SMS_ID
100000081841
Created by admin on Fri Dec 15 16:21:14 GMT 2023 , Edited by admin on Fri Dec 15 16:21:14 GMT 2023
PRIMARY
PUBCHEM
208848
Created by admin on Fri Dec 15 16:21:14 GMT 2023 , Edited by admin on Fri Dec 15 16:21:14 GMT 2023
PRIMARY
NCI_THESAURUS
C65446
Created by admin on Fri Dec 15 16:21:14 GMT 2023 , Edited by admin on Fri Dec 15 16:21:14 GMT 2023
PRIMARY
EPA CompTox
DTXSID10866432
Created by admin on Fri Dec 15 16:21:14 GMT 2023 , Edited by admin on Fri Dec 15 16:21:14 GMT 2023
PRIMARY