DIVABUTEROL

Details

Stereochemistry	RACEMIC
Molecular Formula	C22H35NO5
Molecular Weight	393.517
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(C)NCC(O)C1=CC(OC(=O)C(C)(C)C)=CC(OC(=O)C(C)(C)C)=C1

InChI

InChIKey=VJJOKWOJJZKXNV-UHFFFAOYSA-N

InChI=1S/C22H35NO5/c1-20(2,3)18(25)27-15-10-14(17(24)13-23-22(7,8)9)11-16(12-15)28-19(26)21(4,5)6/h10-12,17,23-24H,13H2,1-9H3

HIDE SMILES / InChI

Description
Sources: Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 1160, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | https://www.ncbi.nlm.nih.gov/pubmed/24277179 | Morton, I.K., Hall, J.M. (2012) Concise Dictionary of Pharmacological Agents, page 270, retrieved from: https://books.google.ru/books?id=tsjrCAAAQBAJ

Divabuterol or terbutaline dipivalate is a prodrug of terbutaline. The half-life of terbutaline dipivalate in human plasma is less than five minutes. Therapeutically, most forms of terbutaline can be used as bronchodilators in antiasthmatic treatment, as smooth muscle relaxants to treat premature labour (uterine relaxant) and for a number of other indications.

Approval Year

PubMed

Title	Date	PubMed
New lipophilic terbutaline ester prodrugs with long effect duration.	1984-01	24277179

Patents

Name

Type

Language

KWD-2085

Preferred Name

English

DIVABUTEROL

Official Name

English

divabuterol [INN]

Common Name

English

(±)-5-(2-(TERT-BUTYLAMINO)-1-HYDROXYETHYL)-M-PHENYLENE DIPIVALATE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C319