Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C28H34FN3O5 |
| Molecular Weight | 511.5851 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)C1=C(CC[C@@H](O)C[C@@H](O)CC(O)=O)N(N=C1C(=O)NCC2=CC=C(C)C=C2)C3=CC=C(F)C=C3
InChI
InChIKey=LRVVTOGAGAXSRZ-DHIUTWEWSA-N
InChI=1S/C28H34FN3O5/c1-17(2)26-24(13-12-22(33)14-23(34)15-25(35)36)32(21-10-8-20(29)9-11-21)31-27(26)28(37)30-16-19-6-4-18(3)5-7-19/h4-11,17,22-23,33-34H,12-16H2,1-3H3,(H,30,37)(H,35,36)/t22-,23-/m1/s1
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Substituted pyrazoles as hepatoselective HMG-CoA reductase inhibitors: discovery of (3R,5R)-7-[2-(4-fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2H-pyrazol-3-yl]-3,5-dihydroxyheptanoic acid (PF-3052334) as a candidate for the treatment of hypercholesterolemia. | 2008-01-10 |
Patents
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887701-48-6
Created by
admin on Mon Mar 31 22:00:42 GMT 2025 , Edited by admin on Mon Mar 31 22:00:42 GMT 2025
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BS6A7ZAD7J
Created by
admin on Mon Mar 31 22:00:42 GMT 2025 , Edited by admin on Mon Mar 31 22:00:42 GMT 2025
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11562549
Created by
admin on Mon Mar 31 22:00:42 GMT 2025 , Edited by admin on Mon Mar 31 22:00:42 GMT 2025
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PRIMARY |
