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Details

Stereochemistry RACEMIC
Molecular Formula C5H6N6.C3H6O3
Molecular Weight 240.2193
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0
Stereo Comments Assumed racemic

SHOW SMILES / InChI
Structure of 2,6-DIAMINOPURINE LACTATE

SMILES

CC(O)C(O)=O.NC1=NC(N)=C2NC=NC2=N1

InChI

InChIKey=AUYOFIBDYBXESB-UHFFFAOYSA-N
InChI=1S/C5H6N6.C3H6O3/c6-3-2-4(9-1-8-2)11-5(7)10-3;1-2(4)3(5)6/h1H,(H5,6,7,8,9,10,11);2,4H,1H3,(H,5,6)

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Hamster and rat fetal cells have low spontaneous mutation frequencies and rates.
2001 Jul 1
Structure-activity relationships of 2'-fluoro-2',3'-unsaturated D-nucleosides as anti-HIV-1 agents.
2002 Mar 14
Crystal structure of calf spleen purine nucleoside phosphorylase in a complex with multisubstrate analogue inhibitor with 2,6-diaminopurine aglycone.
2003 May-Aug
Design, efficient synthesis, and anti-HIV activity of 4'-C-cyano- and 4'-C-ethynyl-2'-deoxy purine nucleosides.
2004
In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir?
2004 Mar
LNA guanine and 2,6-diaminopurine. Synthesis, characterization and hybridization properties of LNA 2,6-diaminopurine containing oligonucleotides.
2004 May 1
Evidence for Watson-Crick and not Hoogsteen or wobble base pairing in the selection of nucleotides for insertion opposite pyrimidines and a thymine dimer by yeast DNA pol eta.
2005 Mar 29
Unrestricted accessibility of short oligonucleotides to RNA.
2005 Sep
Nucleotide analogues with immunobiological properties: 9-[2-Hydroxy-3-(phosphonomethoxy)propyl]-adenine (HPMPA), -2,6-diaminopurine (HPMPDAP), and their N6-substituted derivatives.
2006 Jul 1
Acyclic nucleoside phosphonate antivirals activate gene expression of monocyte chemotactic protein 1 and 3.
2007 Jan
Density functional and experimental studies on the FT-IR and FT-Raman spectra and structure of 2,6-diamino purine and 6-methoxy purine.
2008 Jan
Two specific drugs, BMS-345541 and purvalanol A induce apoptosis of HTLV-1 infected cells through inhibition of the NF-kappaB and cell cycle pathways.
2008 Jun 10
Inhibition of the replication of hepatitis B virus in vitro by a novel 2,6-diaminopurine analog, beta-LPA.
2008 May 2
Reactions of Pd(II) with chelate-tethered 2,6-diaminopurine derivatives: N3-coordination and reaction of the purine system.
2009 Dec 7
Co-expression of recombinant nucleoside phosphorylase from Escherichia coli and its application.
2009 Oct
Effect of substituents on the excited-state dynamics of the modified DNA bases 2,4-diaminopyrimidine and 2,6-diaminopurine.
2010
Comparisons between chemical mapping and binding to isoenergetic oligonucleotide microarrays reveal unexpected patterns of binding to the Bacillus subtilis RNase P RNA specificity domain.
2010 Sep 21
Patents
Name Type Language
2,6-DIAMINOPURINE LACTATE
Systematic Name English
1H-PURINE-2,6-DIAMINE, MONO(2-HYDROXYPROPANOATE)
Common Name English
PROPANOIC ACID, 2-HYDROXY-, COMPD. WITH 9H-PURINE-2,6-DIAMINE (1:1)
Common Name English
Code System Code Type Description
CAS
22194-11-2
Created by admin on Fri Dec 15 15:04:55 GMT 2023 , Edited by admin on Fri Dec 15 15:04:55 GMT 2023
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EPA CompTox
DTXSID20274903
Created by admin on Fri Dec 15 15:04:55 GMT 2023 , Edited by admin on Fri Dec 15 15:04:55 GMT 2023
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PUBCHEM
30975
Created by admin on Fri Dec 15 15:04:55 GMT 2023 , Edited by admin on Fri Dec 15 15:04:55 GMT 2023
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FDA UNII
BL9H86X8PU
Created by admin on Fri Dec 15 15:04:55 GMT 2023 , Edited by admin on Fri Dec 15 15:04:55 GMT 2023
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