Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C21H24BrN5O |
| Molecular Weight | 442.352 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=NC=C(CC2=CNC(NCCCCC3=C(C)C=C(Br)C=N3)=NC2=O)C=C1
InChI
InChIKey=OGEAASSLWZDQBM-UHFFFAOYSA-N
InChI=1S/C21H24BrN5O/c1-14-9-18(22)13-25-19(14)5-3-4-8-23-21-26-12-17(20(28)27-21)10-16-7-6-15(2)24-11-16/h6-7,9,11-13H,3-5,8,10H2,1-2H3,(H2,23,26,27,28)
Temelastine (also known as SK&F 93944) is a competitive histamine H1-receptor antagonist, which does not penetrate the central nervous system. This drug was studied as an anti-allergic agent. Experiments on animals have shown that the drug was efficacious vs. pharmacologic and antigen-induced bronchoconstriction.
CNS Activity
Approval Year
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NCI_THESAURUS |
C29578
Created by
admin on Sat Dec 16 16:29:26 GMT 2023 , Edited by admin on Sat Dec 16 16:29:26 GMT 2023
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100000082446
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C049054
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SUB10882MIG
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CHEMBL70598
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DTXSID60235437
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X-72
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BF6IGI53XH
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55482
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86181-42-2
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C73058
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admin on Sat Dec 16 16:29:26 GMT 2023 , Edited by admin on Sat Dec 16 16:29:26 GMT 2023
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5868
Created by
admin on Sat Dec 16 16:29:26 GMT 2023 , Edited by admin on Sat Dec 16 16:29:26 GMT 2023
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ACTIVE MOIETY
METABOLITE (PARENT)
METABOLITE (PARENT)
