Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | 2C34H37N5O5.C4H6O6 |
| Molecular Weight | 1341.463 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 14 / 14 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O[C@H]([C@@H](O)C(O)=O)C(O)=O.CN1C=C2C[C@H]3N(C)C[C@@H](C=C3C4=C2C1=CC=C4)C(=O)N[C@]5(C)O[C@@]6(O)[C@@H]7CCCN7C(=O)[C@H](CC8=CC=CC=C8)N6C5=O.CN9C=C%10C[C@H]%11N(C)C[C@@H](C=C%11C%12=C%10C9=CC=C%12)C(=O)N[C@]%13(C)O[C@@]%14(O)[C@@H]%15CCCN%15C(=O)[C@H](CC%16=CC=CC=C%16)N%14C%13=O
InChI
InChIKey=JNLPZFZYKSNPFF-DGEBZBOOSA-N
InChI=1S/2C34H37N5O5.C4H6O6/c2*1-33(32(42)39-27(15-20-9-5-4-6-10-20)31(41)38-14-8-13-28(38)34(39,43)44-33)35-30(40)22-16-24-23-11-7-12-25-29(23)21(18-36(25)2)17-26(24)37(3)19-22;5-1(3(7)8)2(6)4(9)10/h2*4-7,9-12,16,18,22,26-28,43H,8,13-15,17,19H2,1-3H3,(H,35,40);1-2,5-6H,(H,7,8)(H,9,10)/t2*22-,26-,27+,28+,33-,34+;1-,2-/m111/s1
Metergotamine (MY-25 or 1-methyl-ergotamine-bitartrate) is a derivative of ergotamine and belongs to peptide alkaloids. It exerts a dampening effect on vessels, in that relaxation is brought about in contracted vessels, whereas contraction is brought in dilated vessels. Metergotamine was being studied in migraine prophylaxis.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Preparedness of Dammam primary health care centers to deal with emergency cases. | 2017-09-22 |
|
| Comparative pharmacokinetic investigations with tritium-labeled ergot alkaloids after oral and intravenous administration man. | 1977-03 |
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| Clinical trial of MY-25 (1-methyl-ergotamine-bitartrate) in migraine prophylaxis. | 1971-10 |
|
| [MY 25, a peroral prophylactic for migraine]. | 1971-06-25 |
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16891-52-4
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123133553
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BA69AZP187
Created by
admin on Tue Apr 01 19:31:37 GMT 2025 , Edited by admin on Tue Apr 01 19:31:37 GMT 2025
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ACTIVE MOIETY
SUBSTANCE RECORD
