Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C20H34O |
| Molecular Weight | 290.4834 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 3 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CO
InChI
InChIKey=OJISWRZIEWCUBN-QIRCYJPOSA-N
InChI=1S/C20H34O/c1-17(2)9-6-10-18(3)11-7-12-19(4)13-8-14-20(5)15-16-21/h9,11,13,15,21H,6-8,10,12,14,16H2,1-5H3/b18-11+,19-13+,20-15+
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Geranylgeraniol potentiates lovastatin inhibition of oncogenic H-Ras processing and signaling while preventing cytotoxicity. | 1997 Jan 23 |
|
| Lovastatin induces apoptosis by inhibiting mitotic and post-mitotic events in cultured mesangial cells. | 1997 Oct 30 |
|
| Fibrate and statin synergistically increase the transcriptional activities of PPARalpha/RXRalpha and decrease the transactivation of NFkappaB. | 2002 Jan 11 |
|
| Simvastatin increases fibrinolytic activity in human peritoneal mesothelial cells independent of cholesterol lowering. | 2002 Nov |
|
| Simvastatin suppresses tissue factor expression and increases fibrinolytic activity in tumor necrosis factor-alpha-activated human peritoneal mesothelial cells. | 2003 Jun |
|
| Lovastatin induces apoptosis of anaplastic thyroid cancer cells via inhibition of protein geranylgeranylation and de novo protein synthesis. | 2003 Sep |
|
| Zoledronic acid up-regulates bone sialoprotein expression in osteoblastic cells through Rho GTPase inhibition. | 2004 Dec 15 |
|
| Lysine beta311 of protein geranylgeranyltransferase type I partially replaces magnesium. | 2004 Jul 16 |
|
| Rosiglitazone upregulates caveolin-1 expression in THP-1 cells through a PPAR-dependent mechanism. | 2004 Nov |
|
| Zoledronic acid treatment impairs protein geranyl-geranylation for biological effects in prostatic cells. | 2006 Mar 15 |
|
| Simvastatin potentiates tumor necrosis factor alpha-mediated apoptosis of human vascular endothelial cells via the inhibition of the geranylgeranylation of RhoA. | 2006 Sep 5 |
|
| Screening of terpenes and derivatives for antimycobacterial activity; identification of geranylgeraniol and geranylgeranyl acetate as potent inhibitors of Mycobacterium tuberculosis in vitro. | 2007 Oct |
|
| Cyr61 downmodulation potentiates the anticancer effects of zoledronic acid in androgen-independent prostate cancer cells. | 2009 Nov 1 |
|
| Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells. | 2010 Mar 1 |
|
| Roles of rat and human aldo-keto reductases in metabolism of farnesol and geranylgeraniol. | 2011 May 30 |
|
| Dysfunction of vascular smooth muscle and vascular remodeling by simvastatin. | 2014 Apr |
Patents
| Name | Type | Language | ||
|---|---|---|---|---|
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
7614-21-3
Created by
admin on Fri Dec 15 17:54:14 GMT 2023 , Edited by admin on Fri Dec 15 17:54:14 GMT 2023
|
PRIMARY | |||
|
GERANYLGERANIOL
Created by
admin on Fri Dec 15 17:54:14 GMT 2023 , Edited by admin on Fri Dec 15 17:54:14 GMT 2023
|
PRIMARY | |||
|
5281365
Created by
admin on Fri Dec 15 17:54:14 GMT 2023 , Edited by admin on Fri Dec 15 17:54:14 GMT 2023
|
PRIMARY | |||
|
AIA02AJA3A
Created by
admin on Fri Dec 15 17:54:14 GMT 2023 , Edited by admin on Fri Dec 15 17:54:14 GMT 2023
|
PRIMARY | |||
|
DTXSID301029793
Created by
admin on Fri Dec 15 17:54:14 GMT 2023 , Edited by admin on Fri Dec 15 17:54:14 GMT 2023
|
PRIMARY | |||
|
46762
Created by
admin on Fri Dec 15 17:54:14 GMT 2023 , Edited by admin on Fri Dec 15 17:54:14 GMT 2023
|
PRIMARY |
SUBSTANCE RECORD
