TEROFENAMATE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C17H17Cl2NO3
Molecular Weight	354.228
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TEROFENAMATE

Structure Search

SMILES

CCOCOC(=O)C1=C(NC2=C(Cl)C(C)=CC=C2Cl)C=CC=C1

InChI

InChIKey=FRQSLQPWXFAJFO-UHFFFAOYSA-N

InChI=1S/C17H17Cl2NO3/c1-3-22-10-23-17(21)12-6-4-5-7-14(12)20-16-13(18)9-8-11(2)15(16)19/h4-9,20H,3,10H2,1-2H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1175762

Terofenamate (or etoclofene), the ethoxy methyl ester of N-(2,6-dichloro-m-tolyl)anthranilic acid, is a non-steroid anti-inflammatory agent. The drug showed a low level of toxicity and was well tolerated in animals.

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
inflammatory response 47 Target ID: GO:0006954 Sources: https://www.ncbi.nlm.nih.gov/pubmed/4460012	Inhibitor 8504

PubMed

PubMed

Title	Date	PubMed
Biological properties of a new non-steroidal anti-inflammatory drug: etoclofene.	1975-05	1175762

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Topical

Name

Type

Language

TEROFENAMATE

Official Name

English

TEROFENAMATE [MI]

Preferred Name

English

terofenamate [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257

Created by admin on Mon Mar 31 18:08:42 GMT 2025 , Edited by admin on Mon Mar 31 18:08:42 GMT 2025

Code System Code Type Description

EPA CompTox

DTXSID20183344

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ChEMBL

CHEMBL2105509

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MERCK INDEX

m1261

Created by admin on Mon Mar 31 18:08:42 GMT 2025 , Edited by admin on Mon Mar 31 18:08:42 GMT 2025

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Merck Index

MESH

C004688

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FDA UNII

A53154FC4N

Created by admin on Mon Mar 31 18:08:42 GMT 2025 , Edited by admin on Mon Mar 31 18:08:42 GMT 2025

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PUBCHEM

65763

Created by admin on Mon Mar 31 18:08:42 GMT 2025 , Edited by admin on Mon Mar 31 18:08:42 GMT 2025

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EVMPD

SUB10930MIG

Created by admin on Mon Mar 31 18:08:42 GMT 2025 , Edited by admin on Mon Mar 31 18:08:42 GMT 2025

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CAS

29098-15-5

Created by admin on Mon Mar 31 18:08:42 GMT 2025 , Edited by admin on Mon Mar 31 18:08:42 GMT 2025

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SMS_ID

100000082712

Created by admin on Mon Mar 31 18:08:42 GMT 2025 , Edited by admin on Mon Mar 31 18:08:42 GMT 2025

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ECHA (EC/EINECS)

249-434-4

Created by admin on Mon Mar 31 18:08:42 GMT 2025 , Edited by admin on Mon Mar 31 18:08:42 GMT 2025

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NCI_THESAURUS

C76818

Created by admin on Mon Mar 31 18:08:42 GMT 2025 , Edited by admin on Mon Mar 31 18:08:42 GMT 2025

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INN

3709

Created by admin on Mon Mar 31 18:08:42 GMT 2025 , Edited by admin on Mon Mar 31 18:08:42 GMT 2025

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ACTIVE MOIETY


					A53154FC4N