PARVAQUONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H16O3
Molecular Weight	256.2964
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PARVAQUONE

Structure Search

SMILES

OC1=C(C2CCCCC2)C(=O)C3=CC=CC=C3C1=O

InChI

InChIKey=JBFUOGRCSLVENL-UHFFFAOYSA-N

InChI=1S/C16H16O3/c17-14-11-8-4-5-9-12(11)15(18)16(19)13(14)10-6-2-1-3-7-10/h4-5,8-10,19H,1-3,6-7H2

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3238773 | https://www.ncbi.nlm.nih.gov/pubmed/6665318

Parvaquone, an antitheilerial compound that was developed for the treatment of East Coast fever. Experiments on animals have shown that this drug was effective in the treatment of cattle infected with Theileria annulata.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Activity of 10 naphthoquinones, including parvaquone (993C) and menoctone, in cattle artificially infected with Theileria parva.	1983 Nov	6665318
Effectiveness of parvaquone in cattle infected with Theileria annulata.	1988 Nov	3238773
Treatment of East Coast fever of cattle with a combination of parvaquone and frusemide.	2004 Apr	15080540

Patents

Patents

Name

Type

Language

PARVAQUONE

Official Name

English

NSC-278

Code

English

PARVAQUONE [MI]

Common Name

English

PARVAQUONE [MART.]

Common Name

English

2-CYCLOHEXYL-3-HYDROXYNAPHTHOQUINONE

Systematic Name

English

parvaquone [INN]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QP51AX21

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NCI_THESAURUS

C271

Created by admin on Sat Dec 16 17:13:20 GMT 2023 , Edited by admin on Sat Dec 16 17:13:20 GMT 2023

Code System Code Type Description

EVMPD

SUB09634MIG

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NSC

278

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SMS_ID

100000083019

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ECHA (EC/EINECS)

223-734-5

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CAS

4042-30-2

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EPA CompTox

DTXSID00877991

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MESH

C028032

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INN

5223

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NCI_THESAURUS

C66327

Created by admin on Sat Dec 16 17:13:20 GMT 2023 , Edited by admin on Sat Dec 16 17:13:20 GMT 2023

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FDA UNII

A2BH18685W

Created by admin on Sat Dec 16 17:13:20 GMT 2023 , Edited by admin on Sat Dec 16 17:13:20 GMT 2023

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ChEMBL

CHEMBL103124

Created by admin on Sat Dec 16 17:13:20 GMT 2023 , Edited by admin on Sat Dec 16 17:13:20 GMT 2023

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MERCK INDEX

m8424

Created by admin on Sat Dec 16 17:13:20 GMT 2023 , Edited by admin on Sat Dec 16 17:13:20 GMT 2023

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Merck Index

ACTIVE MOIETY


					A2BH18685W