Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H10N2O |
| Molecular Weight | 138.1671 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NNCC1=CC=CC(O)=C1
InChI
InChIKey=OFKWWALNMPEOSZ-UHFFFAOYSA-N
InChI=1S/C7H10N2O/c8-9-5-6-2-1-3-7(10)4-6/h1-4,9-10H,5,8H2
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Mechanisms of the effects of exogenous levodopa on the dopamine-denervated striatum. | 2001 |
|
| Stress-induced increase in extracellular dopamine in striatum: role of glutamatergic action via N-methyl-D-aspartate receptors in substantia nigra. | 2001 May 18 |
|
| Promotion of neural cell adhesion by electrochemically generated and functionalized polymer films. | 2001 Nov 15 |
|
| Dopamine autoreceptor regulation of release and uptake in mouse brain slices in the absence of D(3) receptors. | 2002 |
|
| Failure to detect in vivo inverse agonism of the 5-HT(1B) receptor antagonist SB-224289 in 5-HT-depleted guinea-pigs. | 2002 Jun |
|
| Evidence for involvement of 5-hydroxytryptamine(1B) autoreceptors in the enhancement of serotonin turnover in the mouse brain following repeated treatment with fluoxetine. | 2002 Nov 1 |
|
| Chronic hypercortisolemia inhibits dopamine synthesis and turnover in the nucleus accumbens: an in vivo microdialysis study. | 2002 Sep |
|
| Effects of acute, repeated and chronic variable stress on in vivo tyrosine hydroxylase activity and on alpha(2)-adrenoceptor sensitivity in the rat brain. | 2003 Dec |
|
| Serotonergic depression of spinal monosynaptic transmission is mediated by 5-HT1B receptors. | 2003 Dec 15 |
|
| Commonly used L-amino acid decarboxylase inhibitors block monoamine oxidase activity in the rat. | 2003 Mar |
|
| Pharmacology of a novel selective 5-hydroxytryptamine1B receptor antagonist, AR-A000002. | 2004 Mar |
|
| Serotonin reuptake inhibitors do not prevent 5,7-dihydroxytryptamine-induced depletion of serotonin in rat brain. | 2004 May 8 |
|
| Long-term prenatal hypoxia alters maturation of brain catecholaminergic systems and motor behavior in rats. | 2004 Nov |
|
| Neuropeptide Y induced modulation of dopamine synthesis in the striatum. | 2005 Jul 15 |
|
| Dopaminergic mechanisms involved in prolactin release after mifepristone and naloxone treatment during late pregnancy in the rat. | 2006 |
|
| Neuropeptide Y induced attenuation of catecholamine synthesis in the rat mesenteric arterial bed. | 2006 Jun |
|
| Clozapine modulates aromatic L-amino acid decarboxylase activity in mouse striatum. | 2006 May |
|
| Effect of the beta3 adrenoceptor agonist CL 316243 on hypothalamic 5-HT synthesis and suppression of REM sleep in the rat. | 2007 Aug |
|
| Dopaminergic toxicity of the herbicide atrazine in rat striatal slices. | 2007 Mar 22 |
|
| Evidence for serotonin synthesis-dependent regulation of in vitro neuronal firing rates in the midbrain raphe complex. | 2008 Aug 20 |
|
| Amphetamine-evoked rotation requires newly synthesized dopamine at 14 days but not 1 day after intranigral 6-OHDA and is consistently dissociated from sensorimotor behavior. | 2009 Jun 8 |
|
| Alternative splicing and extensive RNA editing of human TPH2 transcripts. | 2010 Jan 29 |
|
| Direct angiotensin II type 2 receptor stimulation decreases dopamine synthesis in the rat striatum. | 2010 Jun |
|
| [Neurochemical study of effects of the new anxiolytic drugs afobazol and ladasten on the synthesis and metabolism of monoamines and their metabolites in the brain structures of Wistar rat on the model of monoamine synthesis blockade induced by aromatic amino acid decarboxylase inhibitor NSD-1015]. | 2010 Mar |
|
| Locomotor response to L-DOPA in reserpine-treated rats following central inhibition of aromatic L-amino acid decarboxylase: further evidence for non-dopaminergic actions of L-DOPA and its metabolites. | 2010 Sep |
Patents
| Name | Type | Language | ||
|---|---|---|---|---|
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| Code System | Code | Type | Description | ||
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A27K5Q85R2
Created by
admin on Sat Dec 16 08:04:33 GMT 2023 , Edited by admin on Sat Dec 16 08:04:33 GMT 2023
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1663
Created by
admin on Sat Dec 16 08:04:33 GMT 2023 , Edited by admin on Sat Dec 16 08:04:33 GMT 2023
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637-33-2
Created by
admin on Sat Dec 16 08:04:33 GMT 2023 , Edited by admin on Sat Dec 16 08:04:33 GMT 2023
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PRIMARY | |||
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DTXSID20213099
Created by
admin on Sat Dec 16 08:04:33 GMT 2023 , Edited by admin on Sat Dec 16 08:04:33 GMT 2023
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PRIMARY |
SUBSTANCE RECORD
