PAPAVEROLINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H13NO4
Molecular Weight	283.2787
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=C(O)C=C(CC2=NC=CC3=CC(O)=C(O)C=C23)C=C1

InChI

InChIKey=MXQKCNCLQIHHJA-UHFFFAOYSA-N

InChI=1S/C16H13NO4/c18-13-2-1-9(6-14(13)19)5-12-11-8-16(21)15(20)7-10(11)3-4-17-12/h1-4,6-8,18-21H,5H2

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7237948

Papaveroline was developed in Italy. It was shown that this compound produced a dose-related inhibition of the aggregation of platelets. This compound is also studied in mental disorders caused by a deficit of non-focalized cerebral circulation. However, information about the further development of papaveroline is not available.

Approval Year

PubMed

Title	Date	PubMed
[Cerebral ischemic vasculopathy: clinical and thermographic study in patients treated with papaveroline].	1981-07-31	7261566
[Papaveroline in mental disorders caused by a deficit of non-focalized cerebral circulation].	1981-01-15	7237948
[Some effects of papaveroline on blood circulation in patients with arteriosclerosis].	1974-05	4619185
[Action of N-methylglucamine, papaveroline and their association on spontaneous motility of isolated arteries].	1969-12	5397155
[Study of the hemodynamic changes induced with a new drug: papaveroline].	1967	5190605

Name

Type

Language

PAPAVEROLINE

Official Name

English

PAPAVEROLINE [MART.]

Preferred Name

English

papaveroline [INN]

Common Name

English

Papaveroline [WHO-DD]

Common Name

English

1-(3,4-DIHYDROXYBENZYL)-6,7-ISOQUINOLINEDIOL

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29707