U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 3Cl.Ga
Molecular Weight 173.287
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GALLIUM CHLORIDE GA-67

SMILES

[Cl-].[Cl-].[Cl-].[67Ga+3]

InChI

InChIKey=UPWPDUACHOATKO-MPZFSRPWSA-K
InChI=1S/3ClH.Ga/h3*1H;/q;;;+3/p-3/i;;;1-3

HIDE SMILES / InChI

Description

Gallium citrate Ga 67 is the citrate salt of the radioisotope gallium Ga 67. Although the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of inflammation, allowing scintigraphic localization. Ga-67 scintigraphy (GS) cannot differentiate between tumor and acute inflammation. Gallium Citrate Ga 67 Injection may be useful in demonstrating the presence of the following malignancies: Hodgkins disease, lymphomas and bronchogenic carcinoma. Positive Ga 67 uptake in the absence of prior symptoms warrants follow-up as an indication of a potential disease state.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
GALLIUM CITRATE GA 67
Primary
GALLIUM CITRATE GA 67
Primary
GALLIUM CITRATE GA 67

Sample Use Guides

In Vivo Use Guide
DOSAGE AND ADMINISTRATION: The recommended adult (70 kg) dose of Gallium Citrate Ga 67 Injection is 74-185 MBq (2-5 mCi). Gallium Citrate Ga 67 Injection is intended for intravenous administration only
Route of Administration: Intravenous