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Details

Stereochemistry ACHIRAL
Molecular Formula C6H11NO2.ClH
Molecular Weight 165.618
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ISONIPECOTIC ACID HYDROCHLORIDE

SMILES

Cl.OC(=O)C1CCNCC1

InChI

InChIKey=NVUYWKBRSRPYMH-UHFFFAOYSA-N
InChI=1S/C6H11NO2.ClH/c8-6(9)5-1-3-7-4-2-5;/h5,7H,1-4H2,(H,8,9);1H

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Alternative splicing of a Drosophila GABA receptor subunit gene identifies determinants of agonist potency.
2001
Zwitterionic 4-piperidinecarboxylic acid monohydrate.
2001 Aug
Phosphinic, phosphonic and seleninic acid bioisosteres of isonipecotic acid as novel and selective GABA(C) receptor antagonists.
2003 Jun
Highly water-soluble derivatives of the anesthetic agent propofol: in vitro and in vivo evaluation of cyclic amino acid esters.
2003 Sep
Characterization and crystal structure of cadmium(II) halide complexes with amino acids and their derivatives VI. The comparison of crystal structures of cadmium(II) halide complexes with three kinds of piperidine carboxylic acids.
2004 Dec
Activation of single heteromeric GABA(A) receptor ion channels by full and partial agonists.
2004 Jun 1
Design, synthesis and anticonvulsive activity of analogs of gamma-vinyl GABA.
2004 May
Temperature effects on the hydrogen-bond patterns in 4-piperidinecarboxylic acid.
2005 Feb
Modifications of the isonipecotic acid fragment of SNS-032: analogs with improved permeability and lower efflux ratio.
2008 Dec 1
Design, synthesis, and structure-activity relationships of piperidine and dehydropiperidine carboxylic acids as novel, potent dual PPARalpha/gamma agonists.
2008 Jun 15
Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
2009 Aug 13
The identification of orally bioavailable thrombopoietin agonists.
2009 Mar 1
Aqua-bis(4-nitro-benzoato)-κO,O';κO-(piperidinium-4-carboxyl-ato-κO,O')cadmium(II).
2009 May 20
Intercepting the synthesis of triazine dendrimers with nucleophilic pharmacophores: a general strategy toward drug delivery vehicles.
2009 Oct 7
Patents
Name Type Language
ISONIPECOTIC ACID HYDROCHLORIDE
MI  
Systematic Name English
ISONIPECOTIC ACID HYDROCHLORIDE [MI]
Common Name English
4-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE
Systematic Name English
4-PIPERIDINECARBOXYLIC ACID, HYDROCHLORIDE
Common Name English
ISONIPECOTIC ACID, HYDROCHLORIDE
Common Name English
4-PIPERIDINECARBOXYLIC ACID, HYDROCHLORIDE (1:1)
Common Name English
Code System Code Type Description
FDA UNII
9Y7QNE4DH3
Created by admin on Fri Dec 15 15:53:28 GMT 2023 , Edited by admin on Fri Dec 15 15:53:28 GMT 2023
PRIMARY
EPA CompTox
DTXSID00208564
Created by admin on Fri Dec 15 15:53:28 GMT 2023 , Edited by admin on Fri Dec 15 15:53:28 GMT 2023
PRIMARY
CAS
5984-56-5
Created by admin on Fri Dec 15 15:53:28 GMT 2023 , Edited by admin on Fri Dec 15 15:53:28 GMT 2023
PRIMARY
PUBCHEM
22298
Created by admin on Fri Dec 15 15:53:28 GMT 2023 , Edited by admin on Fri Dec 15 15:53:28 GMT 2023
PRIMARY
MERCK INDEX
m6505
Created by admin on Fri Dec 15 15:53:28 GMT 2023 , Edited by admin on Fri Dec 15 15:53:28 GMT 2023
PRIMARY Merck Index