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Details

Stereochemistry RACEMIC
Molecular Formula C15H14ClN3O
Molecular Weight 287.744
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DAZADROL

SMILES

OC(C1=NCCN1)(C2=CC=C(Cl)C=C2)C3=NC=CC=C3

InChI

InChIKey=DITYEPYMBCHKLF-UHFFFAOYSA-N
InChI=1S/C15H14ClN3O/c16-12-6-4-11(5-7-12)15(20,14-18-9-10-19-14)13-3-1-2-8-17-13/h1-8,20H,9-10H2,(H,18,19)

HIDE SMILES / InChI

Description

Dazadrol is an antidepressant compound, developed by Schering Corp in the late 1960s. Dazadrol blocks uptake of noradrenaline and inhibits both basal and induced gastric acid secretion in the rat.

Originator

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
Blockade of noradrenaline uptake and inhibition of gastric acid secretion by 2-[p-chlorophenyl-2-(pyridyl)hydroxymethyl] imidazoline maleate (Sch-12650).
1970-05
Patents

Patents

20050002865
228
6680047
81
8158152
108
9016221
110
WO1997041878A1
7
WO2006014484A2
134
WO2007061529A1
72
Name Type Language
DAZADROL
INN  
INN  
Official Name English
.ALPHA.-(P-CHLOROPHENYL)-.ALPHA.-2-IMIDAZOLIN-2-YL-2-PYRIDINEMETHANOL
Preferred Name English
dazadrol [INN]
Common Name English
2-PYRIDINEMETHANOL, .ALPHA.-(4-CHLOROPHENYL)-.ALPHA.-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C265
Created by admin on Mon Mar 31 18:18:12 GMT 2025 , Edited by admin on Mon Mar 31 18:18:12 GMT 2025
Code System Code Type Description
CAS
47029-84-5
Created by admin on Mon Mar 31 18:18:12 GMT 2025 , Edited by admin on Mon Mar 31 18:18:12 GMT 2025
PRIMARY
ChEMBL
CHEMBL2110607
Created by admin on Mon Mar 31 18:18:12 GMT 2025 , Edited by admin on Mon Mar 31 18:18:12 GMT 2025
PRIMARY
INN
3364
Created by admin on Mon Mar 31 18:18:12 GMT 2025 , Edited by admin on Mon Mar 31 18:18:12 GMT 2025
PRIMARY
NCI_THESAURUS
C83654
Created by admin on Mon Mar 31 18:18:12 GMT 2025 , Edited by admin on Mon Mar 31 18:18:12 GMT 2025
PRIMARY
EPA CompTox
DTXSID60866124
Created by admin on Mon Mar 31 18:18:12 GMT 2025 , Edited by admin on Mon Mar 31 18:18:12 GMT 2025
PRIMARY
SMS_ID
100000083464
Created by admin on Mon Mar 31 18:18:12 GMT 2025 , Edited by admin on Mon Mar 31 18:18:12 GMT 2025
PRIMARY
EVMPD
SUB06918MIG
Created by admin on Mon Mar 31 18:18:12 GMT 2025 , Edited by admin on Mon Mar 31 18:18:12 GMT 2025
PRIMARY
ECHA (EC/EINECS)
256-292-7
Created by admin on Mon Mar 31 18:18:12 GMT 2025 , Edited by admin on Mon Mar 31 18:18:12 GMT 2025
PRIMARY
FDA UNII
9U27285V5R
Created by admin on Mon Mar 31 18:18:12 GMT 2025 , Edited by admin on Mon Mar 31 18:18:12 GMT 2025
PRIMARY
PUBCHEM
32940
Created by admin on Mon Mar 31 18:18:12 GMT 2025 , Edited by admin on Mon Mar 31 18:18:12 GMT 2025
PRIMARY
ACTIVE MOIETY
Structure of DAZADROL
SALT/SOLVATE (PARENT)
Structure of DAZADROL MALEATE
NIH
NCATS
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