Details
Stereochemistry | ABSOLUTE |
Molecular Formula | 2C6H7O6.Zn |
Molecular Weight | 415.641 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[Zn++].[H][C@@]1(OC(=O)C(O)=C1[O-])[C@@H](O)CO.[H][C@@]2(OC(=O)C(O)=C2[O-])[C@@H](O)CO
InChI
InChIKey=WWRJFSIRMWUMAE-ZZMNMWMASA-L
InChI=1S/2C6H8O6.Zn/c2*7-1-2(8)5-3(9)4(10)6(11)12-5;/h2*2,5,7-10H,1H2;/q;;+2/p-2/t2*2-,5+;/m00./s1
Zinc Ascorbate can be used as a dietary supplement and as a nutrient. Zinc is an important antioxidant nutrient. It is necessary for protein synthesis, wound healing, for blood stability, normal tissue function, and aids in the digestion and metabolism of phosphorus. It also governs the contractility of muscles and maintains the body’s alkaline balance. Zinc ascorbate has superoxide dismutase-like activity and in vitro antimicrobial activity against Staphylococcus aureus and Escherichia coli. Zinc ascorbate may be effective for acne treatment. Zinc ascorbate inhibits the
growth of P. acnes (MIC, 640 ug/mL).
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL352 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23055762 |
|||
Target ID: CHEMBL354 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23055762 |
|||
Target ID: CHEMBL612639 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23055762 |
|||
Target ID: GO:0072593 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Curative | Unknown Approved UseUnknown |
|||
Primary | Unknown Approved UseUnknown |
|||
Primary | Unknown Approved UseUnknown |
|||
Preventing | Cixtor-Z Approved UseTreatment and prevention of vit C & Zn deficiency. |
Sample Use Guides
In Vivo Use Guide
Sources: http://www.mims.com/philippines/drug/info/cixtor-z
Syr Childn & adolescent 2.5-5 mL (½-1 tsp) once daily. Drops Infant & young childn 0.5-1 mL once daily.
Per 5 mL syr Ascorbic acid (as Na ascorbate) 97.5 mg, Zn (as Zn ascorbate) 9 mg. Per mL drops Ascorbic acid (as Na ascorbate) 45 mg, Zn (as Zn ascorbate) 4.5 mg
Route of Administration:
Oral
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/23055762
MIC of zinc ascorbate was 640 ug/mL against S. aureus and 1280 ug/mL against E. coli.
Name | Type | Language | ||
---|---|---|---|---|
|
Official Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
Classification Tree | Code System | Code | ||
---|---|---|---|---|
|
DSLD |
2524 (Number of products:13)
Created by
admin on Fri Dec 15 18:41:55 GMT 2023 , Edited by admin on Fri Dec 15 18:41:55 GMT 2023
|
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
9TI35313XW
Created by
admin on Fri Dec 15 18:41:55 GMT 2023 , Edited by admin on Fri Dec 15 18:41:55 GMT 2023
|
PRIMARY | |||
|
1549114
Created by
admin on Fri Dec 15 18:41:55 GMT 2023 , Edited by admin on Fri Dec 15 18:41:55 GMT 2023
|
PRIMARY | RxNorm | ||
|
9TI35313XW
Created by
admin on Fri Dec 15 18:41:55 GMT 2023 , Edited by admin on Fri Dec 15 18:41:55 GMT 2023
|
PRIMARY | |||
|
DTXSID50164863
Created by
admin on Fri Dec 15 18:41:55 GMT 2023 , Edited by admin on Fri Dec 15 18:41:55 GMT 2023
|
PRIMARY | |||
|
DB14485
Created by
admin on Fri Dec 15 18:41:55 GMT 2023 , Edited by admin on Fri Dec 15 18:41:55 GMT 2023
|
PRIMARY | |||
|
100000134838
Created by
admin on Fri Dec 15 18:41:55 GMT 2023 , Edited by admin on Fri Dec 15 18:41:55 GMT 2023
|
PRIMARY | |||
|
151728-40-4
Created by
admin on Fri Dec 15 18:41:55 GMT 2023 , Edited by admin on Fri Dec 15 18:41:55 GMT 2023
|
NON-SPECIFIC STOICHIOMETRY | |||
|
SUB66732
Created by
admin on Fri Dec 15 18:41:55 GMT 2023 , Edited by admin on Fri Dec 15 18:41:55 GMT 2023
|
PRIMARY | |||
|
91667835
Created by
admin on Fri Dec 15 18:41:55 GMT 2023 , Edited by admin on Fri Dec 15 18:41:55 GMT 2023
|
PRIMARY | |||
|
331242-75-2
Created by
admin on Fri Dec 15 18:41:55 GMT 2023 , Edited by admin on Fri Dec 15 18:41:55 GMT 2023
|
PRIMARY |
PARENT (SALT/SOLVATE)
SUBSTANCE RECORD