U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C23H32N6O4S
Molecular Weight 488.603
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AILDENAFIL

SMILES

CCCC1=NN(C)C2=C1NC(=NC2=O)C3=CC(=CC=C3OCC)S(=O)(=O)N4C[C@H](C)N[C@H](C)C4

InChI

InChIKey=NFSWSZIPXJAYLR-GASCZTMLSA-N
InChI=1S/C23H32N6O4S/c1-6-8-18-20-21(28(5)27-18)23(30)26-22(25-20)17-11-16(9-10-19(17)33-7-2)34(31,32)29-12-14(3)24-15(4)13-29/h9-11,14-15,24H,6-8,12-13H2,1-5H3,(H,25,26,30)/t14-,15+

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
3.94 nM [IC50]
PubMed

PubMed

TitleDatePubMed
[Aildenafil citrate: a new potent and highly selective phosphodiesterase type 5 inhibitor for the treatment of erectile dysfunction].
2006 Dec
Liquid chromatography tandem mass spectrometry assay to determine the pharmacokinetics of aildenafil in human plasma.
2007 May 9
Name Type Language
AILDENAFIL
Common Name English
METHISOSILDENAFIL
Common Name English
DIMETHYL SILDENAFIL
Common Name English
DIMETHYLSILDENAFIL
Common Name English
7H-PYRAZOLO(4,3-D)PYRIMIDIN-7-ONE, 5-(5-(((3R,5S)-3,5-DIMETHYL-1-PIPERAZINYL)SULFONYL)-2-ETHOXYPHENYL)-1,6-DIHYDRO-1-METHYL-3-PROPYL-, REL-
Systematic Name English
Classification Tree Code System Code
WIKIPEDIA Designer-drugs-Aildenafil
Created by admin on Sat Dec 16 07:59:11 GMT 2023 , Edited by admin on Sat Dec 16 07:59:11 GMT 2023
Code System Code Type Description
CAS
1416130-63-6
Created by admin on Sat Dec 16 07:59:11 GMT 2023 , Edited by admin on Sat Dec 16 07:59:11 GMT 2023
NON-SPECIFIC STEREOCHEMISTRY
PUBCHEM
135452876
Created by admin on Sat Dec 16 07:59:11 GMT 2023 , Edited by admin on Sat Dec 16 07:59:11 GMT 2023
PRIMARY
FDA UNII
9T49W8GAX6
Created by admin on Sat Dec 16 07:59:11 GMT 2023 , Edited by admin on Sat Dec 16 07:59:11 GMT 2023
PRIMARY
CAS
496835-35-9
Created by admin on Sat Dec 16 07:59:11 GMT 2023 , Edited by admin on Sat Dec 16 07:59:11 GMT 2023
PRIMARY
EPA CompTox
DTXSID10197970
Created by admin on Sat Dec 16 07:59:11 GMT 2023 , Edited by admin on Sat Dec 16 07:59:11 GMT 2023
PRIMARY
WIKIPEDIA
AILDENAFIL
Created by admin on Sat Dec 16 07:59:11 GMT 2023 , Edited by admin on Sat Dec 16 07:59:11 GMT 2023
PRIMARY