DIPHENYLAMINE

Possibly Marketed Outside US

First approved in 2010

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H11N
Molecular Weight	169.2224
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

N(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=DMBHHRLKUKUOEG-UHFFFAOYSA-N

InChI=1S/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Inhibition of amiloride-sensitive Na(+) absorption by activation of CFTR in mouse endometrial epithelium.	2001	11845319
Spectroelectrochemical characterization of Si-bridged diphenylamines: influence of Si-bridging upon electronic structures of diphenylamines.	2001 Apr	11990575
Synthesis and antibacterial screening of hydrazones, Schiff and Mannich bases of isatin derivatives.	2001 Jul-Aug	11600231
Adsorption behaviour of some aromatic amines on pyrolusite and activated carbon and recovery of beta napthylamine from water sample.	2001 May	11393426
Expression of cystic fibrosis transmembrane conductance regulator in rat efferent duct epithelium.	2001 May	11319159
First isolation of monomeric N-alkoxyarylaminyl radicals and their chemical and magnetic properties.	2001 Nov 2	11681961
Synthesis and pharmacological activities of hydrazones, Schiff and Mannich bases of isatin derivatives.	2001 Oct	11642321
Dual effect of blocking agents on Ca2+-activated Cl(-) currents in rabbit pulmonary artery smooth muscle cells.	2002 Feb 15	11850506
In-situ spectroelectrochemical evidences for the copolymerization of o-toluidine with diphenylamine-4-sulphonic acid by UV-visible spectroscopy.	2002 Jan 1	11808643
Sphingoid bases and ceramide induce apoptosis in HT-29 and HCT-116 human colon cancer cells.	2002 May	11976405
A quantitative comparison of smokeless measurements.	2002 Nov	12455650
A qualitative comparison of smokeless powder measurements.	2002 Sep	12353587
Synthesis of C60-diphenylaminofluorene dyad with large 2PA cross-sections and efficient intramolecular two-photon energy transfer.	2002 Sep 7	12271642
Screening and characterization of astaxanthin-hyperproducing mutants of Haematococcus pluvialis.	2003 Apr	12882139
Violacein and its beta-cyclodextrin complexes induce apoptosis and differentiation in HL60 cells.	2003 Apr 22	12628314
Evidence of increased DNA content of murine thymocytes caused by cocaine.	2003 Feb	12675199
The effects of immunosuppressants on FAS-mediated activation-induced cell death in human T lymphocytes.	2003 Feb	12595972
Gradient reversed-phase liquid chromatographic-electrospray ionization mass spectrometric method for the comparison of smokeless powders.	2003 Feb 21	12647825
Kinetic enolate formation by lithium arylamide: effects of basicity on selectivity.	2003 Jan 24	12530902
In situ UV-visible spectroelectrochemical evidences for conducting copolymer formation between diphenylamine and m-methoxyaniline.	2003 Jul	12788448
Validation of an in vitro nutrition model using an enteral formula in aged neutrophils.	2003 Jul-Aug	12884475
Inactivation of creatine kinase during the interaction of mefenamic acid with horseradish peroxidase and hydrogen peroxide: participation by the mefenamic acid radical.	2003 Mar 14	12597989
Diphenylamino group as an effective handle to conjugated donor-acceptor polymers through electropolymerization.	2003 Mar 20	12633085
Effect of metabolic factors on apoptosis in thymocytes during tumor growth.	2003 May	12910289
In situ UV-visible spectroelectrochemical studies on the copolymerization of diphenylamine with ortho-methoxy aniline.	2003 May	12714067
Application of a single electrode, modified with polydiphenylamine and dodecyl sulfate, for the simultaneous amperometric determination of electro-inactive anions and cations in ion chromatography.	2003 May 16	12830877
Behavioral effects of rimcazole analogues alone and in combination with cocaine.	2003 May 9	12742518
[In vitro evaluation of the safety and biological activity of recombinant Helicobacter pylori blood group antigen-binding adhesin].	2003 Sep	13129708
Synthesis and structure-activity study of fungicidal anilinopyrimidines leading to mepanipyrim (KIF-3535) as an anti-Botrytis agent.	2004 Apr	15119603
Triaryl boron-based A-pi-A vs triaryl nitrogen-based D-pi-D quadrupolar compounds for single- and two-photon excited fluorescence.	2004 Aug 19	15330651
Novel azido and isothiocyanato analogues of [3-(4-phenylalkylpiperazin-1-yl)propyl]bis(4-fluorophenyl)amines as potential irreversible ligands for the dopamine transporter.	2004 Dec 2	15566284
Orally active anti-proliferation agents: novel diphenylamine derivatives as FGF-R2 autophosphorylation inhibitors.	2004 Feb 23	15012985
Synthesis and functional properties of strongly luminescent diphenylamino end-capped oligophenylenes.	2004 Feb 6	14750823
Photolytic, thermal, addition, and cycloaddition reactions of 2-diazo-5,6- and -3,8-disubstituted acenaphthenones.	2004 Oct 15	15471461
Production of volatile compounds by Fuji apples following exposure to high CO2 or low O2.	2004 Sep 22	15366849
Asymmetric Henry reaction catalyzed by C2-symmetric tridentate bis(oxazoline) and bis(thiazoline) complexes: metal-controlled reversal of enantioselectivity.	2005 Apr 29	15845012
Dual fluorescence of diphenyl carbazide and benzanilide: effect of solvents and pH on electronic spectra.	2005 Dec	16099710
Micell-mediated extraction for the spectrophotometric determination of nitrite in water and biological samples based on its reaction with p-nitroaniline in the presence of diphenylamine.	2005 Jan 15	15620895
Degradation of nitrocellulose by fungi.	2005 Jun	15865147
Diphenylnitrenium ion: cyclization, electron transfer, and polymerization reactions.	2005 Jun 24	15960533
[Apoptosis of phagocytes as one of the probable mechanisms of the pathogenetic action of Yersinia pestis "mouse" toxin].	2005 Mar-Apr	15881939
UV-vis spectroscopy for following the kinetics of homogeneous polymerization of diphenylamine in p-toluene sulphonic acid.	2005 Nov	16257744
Effects of carotenoid inhibition on the photosynthetic RC-LH1 complex in purple sulphur bacterium Thiorhodospira sibirica.	2005 Nov	16172927
Mobile phase influence on electrospray ionization for the analysis of smokeless powders by gradient reversed phase high-performance liquid chromatography-ESIMS.	2005 Nov 25	16182961
Anticancer Drug Discovery and Development - SRI's Seventh Annual Summit.	2005 Oct	16254797
A path to discovery: the career of Maclyn McCarty.	2005 Oct	16207076
Palladium-catalyzed allylation of acidic and less nucleophilic anilines using allylic alcohols directly.	2005 Oct	16204982
Rubber additives induce oxidative stress in rainbow trout.	2005 Oct 15	16144723
BRAF mutation predicts sensitivity to MEK inhibition.	2006 Jan 19	16273091

Patents

Name

Type

Language

DIPHENYLAMINE

Systematic Name

English

N-PHENYLBENZENAMINE

Systematic Name

English

DIPHENYLAMINE [MI]

Common Name

English

STYRENE, REACTION PRODUCT WITH DIPHENYLAMINE

Common Name

English

N,N-DIPHENYLAMINE [HSDB]

Common Name

English

NSC-215210

Code

English

N-PHENYLBENZENEAMINE

Systematic Name

English

STYRENATED DIPHENYLAMINE

Common Name

English

N-PHENYLBENZENAMINE, STYRENATED

Common Name

English

N-PHENYLANILINE

Systematic Name

English

BENZENAMINE, N-PHENYL-, STYRENATED

Common Name

English

Classification Tree Code System Code

CFR

21 CFR 176.170