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Details

Stereochemistry ACHIRAL
Molecular Formula Cr2O7
Molecular Weight 215.988
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge -2

SHOW SMILES / InChI
Structure of DICHROMATE ION

SMILES

[O-][Cr](=O)(=O)O[Cr]([O-])(=O)=O

InChI

InChIKey=SOCTUWSJJQCPFX-UHFFFAOYSA-N
InChI=1S/2Cr.7O/q;;;;;;;2*-1

HIDE SMILES / InChI
Sodium dichromate is an inorganic compound, containing hexavalent chromium. It is highly corrosive and is a strong oxidizing agent. Sodium dichromate is mainly used to produce other chromium compounds but is also used in drilling muds, in metal treatments, in wood preservatives, in the production of dyes and organic chemicals and as a corrosion inhibitor. Sodium dichromate primarily affects the respiratory system causing ulcerations, shortness of breath, bronchitis, pneumonia, and asthma but can also affect the gastrointestinal tract, liver, kidneys and immune system. This substance is a known human carcinogen and is associated with an increased risk of developing lung cancer and cancer of the sinonasal cavity.

Approval Year

PubMed

PubMed

TitleDatePubMed
Effects of Cr(VI) on the expression of the oxidative stress genes in human lung cells.
1998 Aug
Inhibition of protein synthesis by chromium(VI) differentially affects expression of urokinase and its receptor in human type II pneumocytes.
1999 Aug 1
Differential effects of arsenic(III) and chromium(VI) on nuclear transcription factor binding.
1999 Jul
Role of p53 tumor suppressor gene in the toxicity of TCDD, endrin, naphthalene, and chromium (VI) in liver and brain tissues of mice.
2000 Mar 15
The role of hydroxyl radical as a messenger in Cr(VI)-induced p53 activation.
2000 Sep
LLU-alpha, an endogenous metabolite of gamma-tocopherol, is more effective against metal nephrotoxicity in rats than gamma-tocopherol.
2001 Jul 6
Induction of apoptosis in the lung but not in the liver of rats receiving intra-tracheal instillations of chromium(VI).
2002 Apr
Down-regulation of the DNA-repair endonuclease 8-oxo-guanine DNA glycosylase 1 (hOGG1) by sodium dichromate in cultured human A549 lung carcinoma cells.
2002 Jan
Selective induction of gene expression in rat lung by hexavalent chromium.
2002 Oct
NTP toxicity studies of sodium dichromate dihydrate (CAS No. 7789-12-0) administered in drinking water to male and female F344/N rats and B6C3F1 mice and male BALB/c and am3-C57BL/6 mice.
2007 Jan
Exposure to nickel, chromium, or cadmium causes distinct changes in the gene expression patterns of a rat liver derived cell line.
2011
Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90days of exposure to hexavalent chromium in drinking water.
2012 Feb 15
Comparison of the effects of hexavalent chromium in the alimentary canal of F344 rats and B6C3F1 mice following exposure in drinking water: implications for carcinogenic modes of action.
2012 Jan
Inhibitory effect of SJSZ glycoprotein (38 kDa) on expression of heat shock protein 27 and 70 in chromium (VI)-treated hepatocytes.
2012 Jan
Comparative toxicogenomic analysis of oral Cr(VI) exposure effects in rat and mouse small intestinal epithelia.
2012 Jul 15
Whole adult organism transcriptional profiling of acute metal exposures in male zebrafish.
2014 Mar 10
Patents
Name Type Language
DICHROMATE ION
Common Name English
CHROMATE (CR2O72-)
Common Name English
DICHROMATE ION(2-)
Common Name English
DICHROMATE
Systematic Name English
BICHROMATE
Common Name English
CHROMIC ACID (H2CR2O7), ION(2-)
Common Name English
Code System Code Type Description
RXCUI
1313336
Created by admin on Fri Dec 15 17:34:53 UTC 2023 , Edited by admin on Fri Dec 15 17:34:53 UTC 2023
PRIMARY RxNorm
FDA UNII
9LKY4BFN2V
Created by admin on Fri Dec 15 17:34:53 UTC 2023 , Edited by admin on Fri Dec 15 17:34:53 UTC 2023
PRIMARY
EPA CompTox
DTXSID5074004
Created by admin on Fri Dec 15 17:34:53 UTC 2023 , Edited by admin on Fri Dec 15 17:34:53 UTC 2023
PRIMARY
DAILYMED
9LKY4BFN2V
Created by admin on Fri Dec 15 17:34:53 UTC 2023 , Edited by admin on Fri Dec 15 17:34:53 UTC 2023
PRIMARY
PUBCHEM
24503
Created by admin on Fri Dec 15 17:34:53 UTC 2023 , Edited by admin on Fri Dec 15 17:34:53 UTC 2023
PRIMARY
CHEBI
33141
Created by admin on Fri Dec 15 17:34:53 UTC 2023 , Edited by admin on Fri Dec 15 17:34:53 UTC 2023
PRIMARY
DRUG BANK
DB14182
Created by admin on Fri Dec 15 17:34:53 UTC 2023 , Edited by admin on Fri Dec 15 17:34:53 UTC 2023
PRIMARY
CAS
13907-47-6
Created by admin on Fri Dec 15 17:34:53 UTC 2023 , Edited by admin on Fri Dec 15 17:34:53 UTC 2023
PRIMARY