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Details

Stereochemistry ACHIRAL
Molecular Formula C10H11N2O5S.Na
Molecular Weight 294.26
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SULFASUCCINAMIDE SODIUM

SMILES

[Na+].NS(=O)(=O)C1=CC=C(NC(=O)CCC([O-])=O)C=C1

InChI

InChIKey=ZSSBHMSGBSLUHH-UHFFFAOYSA-M
InChI=1S/C10H12N2O5S.Na/c11-18(16,17)8-3-1-7(2-4-8)12-9(13)5-6-10(14)15;/h1-4H,5-6H2,(H,12,13)(H,14,15)(H2,11,16,17);/q;+1/p-1

HIDE SMILES / InChI

Description

Sulfasuccinamide is a sulfonamide antibacterial with properties similar to those of sulfamethoxazole. It has been applied topically in the treatment of local infections of the ear, nose, and throat. It has also been given as the sodium salt. Sulfasuccinamide is a carbonic anhydrase inhibitor.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
0.52 nM [Ki]
6.1 nM [Ki]
12.8 nM [Ki]

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Sulfasuccinamide

PubMed

Sample Use Guides

In Vivo Use Guide
Nasal solution
Route of Administration: Nasal
In Vitro Use Guide
Sulfasuccinamide inhibited human recombinant carbonic anhydrase 12 with Ki value of 0.52 nM. Sulfasuccinamide decreased tumor cell viability of colon HT-29 cells in a concentration-dependent manner (0.01 - 1 mM).