U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C24H32N6O4
Molecular Weight 468.5487
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PF-03049423 FREE BASE

SMILES

CCCOCCN1C(=O)C(=NC2=C1C=C(N=C2)C3=CC=C(OC)N=C3)N4CCN(CCO)CC4

InChI

InChIKey=MNLNAGRCHNMKKJ-UHFFFAOYSA-N
InChI=1S/C24H32N6O4/c1-3-13-34-14-11-30-21-15-19(18-4-5-22(33-2)26-16-18)25-17-20(21)27-23(24(30)32)29-8-6-28(7-9-29)10-12-31/h4-5,15-17,31H,3,6-14H2,1-2H3

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: O76074
Gene ID: 8654.0
Gene Symbol: PDE5A
Target Organism: Homo sapiens (Human)
Name Type Language
PF-03049423 FREE BASE
Code English
PF-5
Code English
PYRIDO(3,4-B)PYRAZIN-2(1H)-ONE, 3-(4-(2-HYDROXYETHYL)-1-PIPERAZINYL)-7-(6-METHOXY-3-PYRIDINYL)-1-(2-PROPOXYETHYL)-
Systematic Name English
Code System Code Type Description
SMS_ID
300000042473
Created by admin on Sat Dec 16 01:41:48 GMT 2023 , Edited by admin on Sat Dec 16 01:41:48 GMT 2023
PRIMARY
FDA UNII
9CZX3Z9945
Created by admin on Sat Dec 16 01:41:48 GMT 2023 , Edited by admin on Sat Dec 16 01:41:48 GMT 2023
PRIMARY
PUBCHEM
24963293
Created by admin on Sat Dec 16 01:41:48 GMT 2023 , Edited by admin on Sat Dec 16 01:41:48 GMT 2023
PRIMARY
CAS
954138-07-9
Created by admin on Sat Dec 16 01:41:48 GMT 2023 , Edited by admin on Sat Dec 16 01:41:48 GMT 2023
PRIMARY