Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C33H52O4 |
| Molecular Weight | 512.7636 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 11 / 11 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCC(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](C[C@@H]5O[C@]6(CC[C@@H](C)CO6)[C@@H](C)[C@H]45)[C@@H]3CC=C2C1
InChI
InChIKey=VMOZFSWFUBLCNN-AAPULDEBSA-N
InChI=1S/C33H52O4/c1-6-7-8-9-29(34)36-24-13-15-31(4)23(18-24)10-11-25-26(31)14-16-32(5)27(25)19-28-30(32)22(3)33(37-28)17-12-21(2)20-35-33/h10,21-22,24-28,30H,6-9,11-20H2,1-5H3/t21-,22+,24+,25-,26+,27+,28+,30+,31+,32+,33-/m1/s1
Caprospinol, also known as SP-233, a spirostenol derivative, protects neuronal cells against β-Amyloid (Abeta(1-42)) protein toxicity by binding to and inactivating this peptide. It was shown, that caprospinol crossed the blood-brain barrier, accumulated in the brain, and restored cognitive impairment in a pharmacological rat model of Alzheimer's disease. It was suggested, that the drug could be considered as a promising drug for Alzheimer's disease treatment.
Approval Year
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16394575
Created by
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DB05263
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9BU4T267E4
Created by
admin on Mon Mar 31 22:46:11 GMT 2025 , Edited by admin on Mon Mar 31 22:46:11 GMT 2025
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4952-56-1
Created by
admin on Mon Mar 31 22:46:11 GMT 2025 , Edited by admin on Mon Mar 31 22:46:11 GMT 2025
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SUBSTANCE RECORD
