Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C10H13ClN4 |
| Molecular Weight | 224.69 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=NN=C(C=C1)N2C[C@@H]3CC[C@H](C2)N3
InChI
InChIKey=USXYDBGSWSSTGE-OCAPTIKFSA-N
InChI=1S/C10H13ClN4/c11-9-3-4-10(14-13-9)15-5-7-1-2-8(6-15)12-7/h3-4,7-8,12H,1-2,5-6H2/t7-,8+
DescriptionCurator's Comment: Description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/9513595 | http://onlinelibrary.wiley.com/doi/10.1002/(SICI)1098-2299(199703)40:3%3C251::AID-DDR5%3E3.0.CO;2-J/abstract | http://onlinelibrary.wiley.com/doi/10.1002/(SICI)1098-2299(199810)45:2%3C45::AID-DDR1%3E3.0.CO;2-Q/full
Curator's Comment: Description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/9513595 | http://onlinelibrary.wiley.com/doi/10.1002/(SICI)1098-2299(199703)40:3%3C251::AID-DDR5%3E3.0.CO;2-J/abstract | http://onlinelibrary.wiley.com/doi/10.1002/(SICI)1098-2299(199810)45:2%3C45::AID-DDR1%3E3.0.CO;2-Q/full
DBO-83 is a 3,8-diazabicyclo[3.2.1]octane derivative with
antinociceptive properties. DBO-83 exhibits high affinity for the α4β2 subtype and is a full agonist at α4β2 and ganglionic receptors but lacks appreciable activity at neuromuscular receptors. DBO-83 exhibits antinociceptive activity in both rat and mouse models of acute and persistent
pain. In addition DBO-83 modulates memory functions in rodents.
Originator
Approval Year
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286946-32-5
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6603824
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DTXSID80423410
Created by
admin on Mon Mar 31 22:04:08 GMT 2025 , Edited by admin on Mon Mar 31 22:04:08 GMT 2025
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98V4V8YB1T
Created by
admin on Mon Mar 31 22:04:08 GMT 2025 , Edited by admin on Mon Mar 31 22:04:08 GMT 2025
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ACTIVE MOIETY
SALT/SOLVATE (PARENT)
