NIFURTOINOL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H8N4O6
Molecular Weight	268.183
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of NIFURTOINOL

Structure Search

SMILES

OCN1C(=O)CN(\N=C\C2=CC=C(O2)[N+]([O-])=O)C1=O

InChI

InChIKey=UIDWQGRXEVDFCA-XCVCLJGOSA-N

InChI=1S/C9H8N4O6/c14-5-11-7(15)4-12(9(11)16)10-3-6-1-2-8(19-6)13(17)18/h1-3,14H,4-5H2/b10-3+

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7113858 | https://www.ncbi.nlm.nih.gov/pubmed/3371877

Nifurtoinol, a nitrofuran-derivative, is an antibacterial drug. Nifurtoinol (Urfadyn PL) is used for the treatment of urinary tract infections. Nifurtoinol-associated hepatic injury cases were reported in Netherlands.

Approval Year

Patents

Patents

Sample Use Guides

In Vivo Use Guide

Adult: Up to 300 mg daily in divided doses.

Route of Administration: Oral

Name

Type

Language

URFADYN

Preferred Name

English

NIFURTOINOL

Official Name

English

NIFURTOINOL [MI]

Common Name

English

Nifurtoinol [WHO-DD]

Common Name

English

nifurtoinol [INN]

Common Name

English

NIFURTOINOL [MART.]

Common Name

English

3-(HYDROXYMETHYL)-1-((5-NITROFURFURYLIDENE)AMINO)HYDANTOIN

Systematic Name

English

Classification Tree Code System Code

WHO-ATC

J01XE02

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NCI_THESAURUS

C255

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WHO-VATC

QJ01XE02

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Code System Code Type Description

DRUG BANK

DB13730

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MESH

C002848

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ECHA (EC/EINECS)

214-126-0

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DRUG CENTRAL

1930

Created by admin on Mon Mar 31 18:28:32 GMT 2025 , Edited by admin on Mon Mar 31 18:28:32 GMT 2025

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WIKIPEDIA

Nifurtoinol

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PUBCHEM

9571062

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MERCK INDEX

m7893

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Merck Index

EVMPD

SUB09281MIG

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EPA CompTox

DTXSID30148747

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FDA UNII

980688H13O

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ChEMBL

CHEMBL1697763

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CAS

1088-92-2

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NCI_THESAURUS

C90997

Created by admin on Mon Mar 31 18:28:32 GMT 2025 , Edited by admin on Mon Mar 31 18:28:32 GMT 2025

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INN

3997

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SMS_ID

100000083898

Created by admin on Mon Mar 31 18:28:32 GMT 2025 , Edited by admin on Mon Mar 31 18:28:32 GMT 2025

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ACTIVE MOIETY


					980688H13O