U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C23H23N5O
Molecular Weight 385.4616
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FR-194921

SMILES

CN1CCC(CC1)N2N=C(C=CC2=O)C3=C4C=CC=CN4N=C3C5=CC=CC=C5

InChI

InChIKey=YHDRUTMZCJZJAL-UHFFFAOYSA-N
InChI=1S/C23H23N5O/c1-26-15-12-18(13-16-26)28-21(29)11-10-19(24-28)22-20-9-5-6-14-27(20)25-23(22)17-7-3-2-4-8-17/h2-11,14,18H,12-13,15-16H2,1H3

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Synthesis and evaluation of [11C]FR194921 as a nonxanthine-type PET tracer for adenosine A1 receptors in the brain.
2005-11
Pharmacological characterization of FR194921, a new potent, selective, and orally active antagonist for central adenosine A1 receptors.
2004-09
Name Type Language
3(2H)-PYRIDAZINONE, 2-(1-METHYL-4-PIPERIDINYL)-6-(2-PHENYLPYRAZOLO(1,5-A)PYRIDIN-3-YL)-
Preferred Name English
FR-194921
Common Name English
Code System Code Type Description
PUBCHEM
9821511
Created by admin on Mon Mar 31 22:36:20 GMT 2025 , Edited by admin on Mon Mar 31 22:36:20 GMT 2025
PRIMARY
FDA UNII
9765J8QB7Q
Created by admin on Mon Mar 31 22:36:20 GMT 2025 , Edited by admin on Mon Mar 31 22:36:20 GMT 2025
PRIMARY
CAS
202646-80-8
Created by admin on Mon Mar 31 22:36:20 GMT 2025 , Edited by admin on Mon Mar 31 22:36:20 GMT 2025
PRIMARY