Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C17H20O4 |
| Molecular Weight | 288.3383 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(=O)O[C@H]1C[C@@H]2[C@@H]([C@H]3OC(=O)C(=C)[C@@H]3CCC2=C)C1=C
InChI
InChIKey=GKMFOEIZCLMZDE-QXKUPLGCSA-N
InChI=1S/C17H20O4/c1-8-5-6-12-9(2)17(19)21-16(12)15-10(3)14(7-13(8)15)20-11(4)18/h12-16H,1-3,5-7H2,4H3/t12-,13-,14-,15-,16-/m0/s1
Zaluzanin D is a sesquiterpene lactone that has been isolated from the aerial parts of Vernonia arborea as a major constituent (0.04%). Zaluzanin D isolated from laurel (Laurus nobilis L.) has being shown to induce cell death and morphological change indicative of apoptotic chromatin condensation in leukemia HL-60 cells. Zaluzanin D demonstrated antibacterial activity against Bacillus subtilis and Staphylococcus aureus.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Sesquiterpenes (costunolide and zaluzanin D) isolated from laurel (Laurus nobilis L.) induce cell death and morphological change indicative of apoptotic chromatin condensation in leukemia HL-60 cells. | 2003-08 |
|
| Zaluzanin D: a fungistatic sesquiterpene from Vernonia arborea. | 2003-07 |
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
DTXSID80168556
Created by
admin on Mon Mar 31 20:12:12 GMT 2025 , Edited by admin on Mon Mar 31 20:12:12 GMT 2025
|
PRIMARY | |||
|
12445012
Created by
admin on Mon Mar 31 20:12:12 GMT 2025 , Edited by admin on Mon Mar 31 20:12:12 GMT 2025
|
PRIMARY | |||
|
96A1V1GV0X
Created by
admin on Mon Mar 31 20:12:12 GMT 2025 , Edited by admin on Mon Mar 31 20:12:12 GMT 2025
|
PRIMARY | |||
|
16838-85-0
Created by
admin on Mon Mar 31 20:12:12 GMT 2025 , Edited by admin on Mon Mar 31 20:12:12 GMT 2025
|
PRIMARY |
SUBSTANCE RECORD
