Details
Stereochemistry | ACHIRAL |
Molecular Formula | 2C2H3O2.Cd |
Molecular Weight | 230.499 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[Cd++].CC([O-])=O.CC([O-])=O
InChI
InChIKey=LHQLJMJLROMYRN-UHFFFAOYSA-L
InChI=1S/2C2H4O2.Cd/c2*1-2(3)4;/h2*1H3,(H,3,4);/q;;+2/p-2
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
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Target ID: human serum albumin aggregation Sources: https://www.ncbi.nlm.nih.gov/pubmed/24771482 |
PubMed
Title | Date | PubMed |
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Nerve growth factor-stimulated calcium uptake into PC12 cells: uniqueness of the channel and evidence for phosphorylation. | 1992 Apr |
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Induction of orphan nuclear receptor Nur77 gene expression and its role in cadmium-induced apoptosis in lung. | 2004 Aug |
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Cadmium induces apoptotic cell death in WI 38 cells via caspase-dependent Bid cleavage and calpain-mediated mitochondrial Bax cleavage by Bcl-2-independent pathway. | 2004 Nov 1 |
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Effects of cadmium exposure on testis apoptosis in the marine teleost Gobius niger. | 2005 May 15 |
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Integrating time-course microarray gene expression profiles with cytotoxicity for identification of biomarkers in primary rat hepatocytes exposed to cadmium. | 2006 Jan 1 |
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Biochemical and molecular effects of gestational and lactational coexposure to lead and cadmium on ovarian steroidogenesis are associated with oxidative stress in F1 generation rats. | 2010 Nov-Dec |
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Pre-treatment with N-acetylcysteine upregulates superoxide dismutase 2 and catalase genes in cadmium-induced oxidative stress in the chick omphalocele model. | 2011 Feb |
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Cadmium-induced up-regulation of aldo-keto reductase 1C3 expression in human nasal septum carcinoma RPMI-2650 cells: Involvement of reactive oxygen species and phosphatidylinositol 3-kinase/Akt. | 2011 May |
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Protective effects of quercetin on cadmium-induced cytotoxicity in primary cultures of rat proximal tubular cells. | 2013 Apr |
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Disturbance of SHH signalling pathway during early embryogenesis in the cadmium-induced omphalocele chick model. | 2013 Feb |
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Regulation of the high-affinity copper transporter (hCtr1) expression by cisplatin and heavy metals. | 2014 Jan |
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Cadmium induces PC12 cells apoptosis via an extracellular signal-regulated kinase and c-Jun N-terminal kinase-mediated mitochondrial apoptotic pathway. | 2014 May |
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Critical cysteines in Akt1 regulate its activity and proteasomal degradation: implications for neurodegenerative diseases. | 2014 Sep |
Patents
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m2889
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543-90-8
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95KC50Z1L0
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SUBSTANCE RECORD