Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C16H20N4O2.ClH |
| Molecular Weight | 336.817 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.[H][C@]12CC[C@]([H])(C[C@@H](C1)NC(=O)N3C(=O)NC4=CC=CC=C34)N2C
InChI
InChIKey=WKDOOXQPGYZUKZ-XSYYVRJTSA-N
InChI=1S/C16H20N4O2.ClH/c1-19-11-6-7-12(19)9-10(8-11)17-15(21)20-14-5-3-2-4-13(14)18-16(20)22;/h2-5,10-12H,6-9H2,1H3,(H,17,21)(H,18,22);1H/t10-,11+,12-;
DescriptionCurator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/8891590
Curator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/8891590
DAU 6215 (Itasetron) is a selective 5-hydroxytryptamine3 (5-HT3) antagonist, which was developed by Boehringer Ingelheim. And was investigated for treatment the nausea and vomiting induced by chemotherapy, it was confirmed that this drug possessed antiemetic properties. Also was discovered, that chronic treatment with itasetron significantly improved retention abilities of the aged rats in this memory test. However, development of itasetron was terminated.
Approval Year
Sample Use Guides
Nausea and vomiting: itasetron hydrochloride is effective in the dose range 35-280 microg/kg in preventing cisplatin-induced emesis.
Route of Administration:
Intravenous
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Code | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
127618-28-4
Created by
admin on Sat Dec 16 07:39:33 GMT 2023 , Edited by admin on Sat Dec 16 07:39:33 GMT 2023
|
PRIMARY | |||
|
m1199
Created by
admin on Sat Dec 16 07:39:33 GMT 2023 , Edited by admin on Sat Dec 16 07:39:33 GMT 2023
|
PRIMARY | Merck Index | ||
|
DTXSID30925919
Created by
admin on Sat Dec 16 07:39:33 GMT 2023 , Edited by admin on Sat Dec 16 07:39:33 GMT 2023
|
PRIMARY | |||
|
958C27ZK8Y
Created by
admin on Sat Dec 16 07:39:33 GMT 2023 , Edited by admin on Sat Dec 16 07:39:33 GMT 2023
|
PRIMARY |
ACTIVE MOIETY
SUBSTANCE RECORD
