SARCOLYSINE, D-

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C13H18Cl2N2O2
Molecular Weight	305.2
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

N[C@H](CC1=CC=C(C=C1)N(CCCl)CCCl)C(O)=O

InChI

InChIKey=SGDBTWWWUNNDEQ-GFCCVEGCSA-N

InChI=1S/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m1/s1

HIDE SMILES / InChI

Description
Sources: https://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm?archiveid=13952

The D-isomer of melphalan, known as medphalan, is less active against certain animal tumors and the dose needed to produce effects on chromosomes is larger than that required with the L-isomer.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
[Anti-tumor activity of optic isomers of sarcolysin].	1958 Sep	13607541

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Name

Type

Language

SARCOLYSINE, D-

Common Name

English

CB-3026

Code

English

MEDPHALAN

Common Name

English

MELPHALAN D-FORM [MI]

Common Name

English

D-PHENYLALANINE, 4-(BIS(2-CHLOROETHYL)AMINO)-

Systematic Name

English

D-SARCOLYSINE

Common Name

English

MEDPHALAN [IARC]

Common Name

English

D-PHENYLALANINE MUSTARD

Common Name

English

D-MELPHALAN

Common Name

English

NSC-35051

Code

English

MELPHALAN, D-

Common Name

English

Code System Code Type Description

PUBCHEM

20189