PINACYANOL IODIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C25H25N2.I
Molecular Weight	480.3839
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	2
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[I-].CCN1\C(=C/C=C/C2=CC=C3C=CC=CC3=[N+]2CC)C=CC4=C1C=CC=C4

InChI

InChIKey=QWYZFXLSWMXLDM-UHFFFAOYSA-M

InChI=1S/C25H25N2.HI/c1-3-26-22(18-16-20-10-5-7-14-24(20)26)12-9-13-23-19-17-21-11-6-8-15-25(21)27(23)4-2;/h5-19H,3-4H2,1-2H3;1H/q+1;/p-1

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Description
Sources: Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 1301, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 514, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | Zaborszky, L., Wouterlood, F.G., Lanciego, J.L. (2006) Neuroanatomical Tract-Tracing, page 367, retrieved from: https://books.google.ru/books?id=-vPcRekAT6oC | https://www.scbt.com/scbt/product/1-1prime-diethyl-2-2prime-carbocyanine-iodide-605-91-4

Pinacyanol iodide is a fluorescent cationic cyanine dye used to stain biological specimens. It is the obstetric diagnostic aid. The mechanism of tracing with pinacyanol iodide dyes is based on their lipid solubility. Pinacyanol iodide dyes are more efficacious than classical tracing methodologies especially during early stages of development and consequently have been used to reveal the spatiotemporal patterns of axonal development in different species. The unique properties of the pinacyanol iodide dye tracing method have opened up new avenues for tracing connections in human postmortem specimens. Pinacyanol iodide dye tracing is incompatible with alcohol fixation and paraffin embedding of tissue.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Staphylococcus aureus 70 Target ID: CHEMBL352 Sources: https://www.ncbi.nlm.nih.gov/pubmed/28930155	Inhibitor 8504
Amyloid beta-Peptide 2 Target ID: Amyloid beta-Peptide Sources: https://www.ncbi.nlm.nih.gov/pubmed/14587068	Binding Agent 1076

Name

Type

Language

G-1700

Preferred Name

English

PINACYANOL IODIDE

Common Name

English

QUINOLINIUM, 1-ETHYL-2-(3-(1-ETHYL-2(1H)-QUINOLINYLIDENE)-1-PROPEN-1-YL)-, IODIDE (1:1)

Systematic Name

English

NSC-403532

Code

English

CARBOCYANINE

Common Name

English

NK-3

Code

English

Code System Code Type Description

CHEBI

52218