Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C55H78FN9O8 |
| Molecular Weight | 1012.2617 |
| Optical Activity | UNSPECIFIED |
| Additional Stereochemistry | Yes |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Charge | 0 |
| Stereo Comments | AXIAL, (M) |
SHOW SMILES / InChI
SMILES
CCN1C2=C3C=C(C=C2)N4CCO[C@H](C4)C[C@H](NC(=O)[C@H](C(C)C)N(C)C(=O)C5(F)CCN(CC5)C(=O)C#CC(C)(C)N(C)C)C(=O)N6CCC[C@H](N6)C(=O)OCC(C)(C)CC3=C1C7=C(N=CC=C7)[C@H](C)OC
InChI
InChIKey=HJNFYLSFWYRSHS-CMZSUCOPSA-N
InChI=1S/C55H78FN9O8/c1-13-64-44-19-18-37-30-40(44)41(48(64)39-16-14-24-57-46(39)36(4)71-12)32-53(5,6)34-73-51(69)42-17-15-25-65(59-42)50(68)43(31-38-33-63(37)28-29-72-38)58-49(67)47(35(2)3)61(11)52(70)55(56)22-26-62(27-23-55)45(66)20-21-54(7,8)60(9)10/h14,16,18-19,24,30,35-36,38,42-43,47,59H,13,15,17,22-23,25-29,31-34H2,1-12H3,(H,58,67)/t36-,38-,42-,43-,47-/m0/s1
Approval Year
Cmax
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
250 nM |
300 mg single, oral dose: 300 mg route of administration: Oral experiment type: SINGLE co-administered: |
RMC-6291 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
AUC
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
740 nM × h |
300 mg single, oral dose: 300 mg route of administration: Oral experiment type: SINGLE co-administered: |
RMC-6291 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
T1/2
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
1.82 h |
300 mg single, oral dose: 300 mg route of administration: Oral experiment type: SINGLE co-administered: |
RMC-6291 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
| Name | Type | Language | ||
|---|---|---|---|---|
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Official Name | English | ||
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Preferred Name | English | ||
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Systematic Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
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2641998-63-0
Created by
admin on Wed Apr 02 15:54:52 GMT 2025 , Edited by admin on Wed Apr 02 15:54:52 GMT 2025
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156336120
Created by
admin on Wed Apr 02 15:54:52 GMT 2025 , Edited by admin on Wed Apr 02 15:54:52 GMT 2025
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13269
Created by
admin on Wed Apr 02 15:54:52 GMT 2025 , Edited by admin on Wed Apr 02 15:54:52 GMT 2025
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942KVV5CJP
Created by
admin on Wed Apr 02 15:54:52 GMT 2025 , Edited by admin on Wed Apr 02 15:54:52 GMT 2025
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PRIMARY |
ACTIVE MOIETY
