Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C24H34O5 |
Molecular Weight | 402.5238 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 6 / 6 |
E/Z Centers | 1 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@]12C[C@@H](O)[C@H](C#C[C@@H](O)[C@@H](C)CC#CCC)[C@@]1([H])C\C(C2)=C\COCCCC(O)=O
InChI
InChIKey=MAUUNYHAXGTMMQ-AMXXQSRZSA-N
InChI=1S/C24H34O5/c1-3-4-5-7-17(2)22(25)10-9-20-21-15-18(14-19(21)16-23(20)26)11-13-29-12-6-8-24(27)28/h11,17,19-23,25-26H,3,6-8,12-16H2,1-2H3,(H,27,28)/b18-11+/t17-,19-,20+,21-,22+,23+/m0/s1
Eptaloprost is a novel concept PGI2-mimetic, which is designed to be activated to the pharmacologically potent cicaprost via beta-oxidation. Eptaloprost has a significant antimetastatic activity in a spontaneously metastasizing tumor model. Eptaloprost was undergoing phase I clinical trials with Schering AG in Germany for the treatment of cardiovascular disorders.
Originator
Approval Year
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NCI_THESAURUS |
C78568
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93X6A56W84
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C067428
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CHEMBL2105604
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DTXSID70869060
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90693-76-8
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100000084557
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C65523
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SUB06592MIG
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5825
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6436047
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ACTIVE MOIETY