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Details

Stereochemistry ACHIRAL
Molecular Formula C3H4O4
Molecular Weight 104.0615
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of HYDROXYPYRUVIC ACID

SMILES

OCC(=O)C(O)=O

InChI

InChIKey=HHDDCCUIIUWNGJ-UHFFFAOYSA-N
InChI=1S/C3H4O4/c4-1-2(5)3(6)7/h4H,1H2,(H,6,7)

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Potential cytotoxic effect of hydroxypyruvate produced from D-serine by astroglial D-amino acid oxidase.
2010-12
Metabolism gets lucky.
2010-11-30
Three serendipitous pathways in E. coli can bypass a block in pyridoxal-5'-phosphate synthesis.
2010-11-30
Structural insights into substrate specificity in variants of N-acetylneuraminic Acid lyase produced by directed evolution.
2010-11-19
Mitochondrial malate dehydrogenase lowers leaf respiration and alters photorespiration and plant growth in Arabidopsis.
2010-11
Methanol assimilation in Methylobacterium extorquens AM1: demonstration of all enzymes and their regulation.
2010-10-01
Comparative analysis of proteome maps of silkworm hemolymph during different developmental stages.
2010-09-08
Differential proteomic response to heat stress in thermal Agrostis scabra and heat-sensitive Agrostis stolonifera.
2010-06-01
Glyoxylate rather than ascorbate is an efficient precursor for oxalate biosynthesis in rice.
2010-06
Tricarboxylic acid cycle activity regulates tomato root growth via effects on secondary cell wall production.
2010-06
Identification of the 2-hydroxyglutarate and isovaleryl-CoA dehydrogenases as alternative electron donors linking lysine catabolism to the electron transport chain of Arabidopsis mitochondria.
2010-05
Structure and substrate docking of a hydroxy(phenyl)pyruvate reductase from the higher plant Coleus blumei Benth.
2010-05
Transcriptional profiling of an Fd-GOGAT1/GLU1 mutant in Arabidopsis thaliana reveals a multiple stress response and extensive reprogramming of the transcriptome.
2010-03-22
In silico feasibility of novel biodegradation pathways for 1,2,4-trichlorobenzene.
2010-02-02
Fatty acid beta-oxidation in germinating Arabidopsis seeds is supported by peroxisomal hydroxypyruvate reductase when malate dehydrogenase is absent.
2010-01
Beyond the dopamine receptor: novel therapeutic targets for treating schizophrenia.
2010
The Role of PPARα Activation in Liver and Muscle.
2010
Potential diagnostic biomarkers in serum of idiopathic pulmonary arterial hypertension.
2009-12
Design and characterization of a prototype enzyme microreactor: quantification of immobilized transketolase kinetics.
2009-11-21
Halogenated pyruvate derivatives as substrates of transketolase from Saccharomyces cerevisiae.
2009-11
Assay of alanine:glyoxylate aminotransferase in human liver by its serine: glyoxylate aminotransferase activity.
2009-10
Role of plant glyoxylate reductases during stress: a hypothesis.
2009-09-14
Low concentration of anti-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene induces alterations of extracellular protein profile of exposed epithelial cells.
2009-09
X-ray crystal structure of GarR-tartronate semialdehyde reductase from Salmonella typhimurium.
2009-09
Parallel expression evolution of oxidative stress-related genes in fiber from wild and domesticated diploid and polyploid cotton (Gossypium).
2009-08-17
Detection of a gem-diamine and a stable quinonoid intermediate in the reaction catalyzed by serine-glyoxylate aminotransferase from Hyphomicrobium methylovorum.
2009-06
Efficient reconstruction of metabolic pathways by bidirectional chemical search.
2009-04
Influence of Honey on the Suppression of Human Low Density Lipoprotein (LDL) Peroxidation (In vitro).
2009-03
Exploring and dissecting genome-wide gene expression responses of Penicillium chrysogenum to phenylacetic acid consumption and penicillinG production.
2009-02-10
Subcellular localization and enzymatic properties of differentially expressed transketolase genes isolated from the desiccation tolerant resurrection plant Craterostigma plantagineum.
2009-02
Shoot-specific down-regulation of protein farnesyltransferase (alpha-subunit) for yield protection against drought in canola.
2009-01
Methylobacterium genome sequences: a reference blueprint to investigate microbial metabolism of C1 compounds from natural and industrial sources.
2009
Conserved main-chain peptide distortions: a proposed role for Ile203 in catalysis by dihydrodipicolinate synthase.
2008-12
A cytosolic pathway for the conversion of hydroxypyruvate to glycerate during photorespiration in Arabidopsis.
2008-10
Peroxisomal malate dehydrogenase is not essential for photorespiration in Arabidopsis but its absence causes an increase in the stoichiometry of photorespiratory CO2 release.
2008-10
Identification and functional analysis of light-responsive unique genes and gene family members in rice.
2008-08-22
Structural analysis of substrate and effector binding in Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase.
2008-08-12
Complete genome sequence of the extremely acidophilic methanotroph isolate V4, Methylacidiphilum infernorum, a representative of the bacterial phylum Verrucomicrobia.
2008-07-01
Molecular cloning and characterization of Plasmodium falciparum transketolase.
2008-07
Time-resolved metabolomics reveals metabolic modulation in rice foliage.
2008-06-18
Metaproteomics provides functional insight into activated sludge wastewater treatment.
2008-03-12
Metabolism of halophilic archaea.
2008-03
Development of a broad-host-range sacB-based vector for unmarked allelic exchange.
2008-02-26
Properties of serine:glyoxylate aminotransferase purified from Arabidopsis thaliana leaves.
2008-02
A model for carbohydrate metabolism in the diatom Phaeodactylum tricornutum deduced from comparative whole genome analysis.
2008-01-09
Evolutionary analysis of the TPP-dependent enzyme family.
2008-01
Whole genome transcriptome polymorphisms in Arabidopsis thaliana.
2008
Gamma-hydroxybutyrate accumulation in Arabidopsis and tobacco plants is a general response to abiotic stress: putative regulation by redox balance and glyoxylate reductase isoforms.
2008
Identification and characterization of a plastid-localized Arabidopsis glyoxylate reductase isoform: comparison with a cytosolic isoform and implications for cellular redox homeostasis and aldehyde detoxification.
2008
Isolation of glyoxysomes from pumpkin cotyledons.
2006-01
Name Type Language
FEMA NO. 3843
Preferred Name English
HYDROXYPYRUVIC ACID
Systematic Name English
3-HYDROXY-2-OXOPROPANOIC ACID [FHFI]
Common Name English
3-HYDROXYPYRUVIC ACID
Common Name English
PROPANOIC ACID, 3-HYDROXY-2-OXO-
Common Name English
.BETA.-HYDROXYPYRUVIC ACID
Systematic Name English
2-OXO-3-HYDROXYPROPIONIC ACID
Systematic Name English
PYRUVIC ACID, HYDROXY-
Common Name English
Code System Code Type Description
CAS
1113-60-6
Created by admin on Mon Mar 31 19:58:49 GMT 2025 , Edited by admin on Mon Mar 31 19:58:49 GMT 2025
PRIMARY
FDA UNII
934B2KHY0S
Created by admin on Mon Mar 31 19:58:49 GMT 2025 , Edited by admin on Mon Mar 31 19:58:49 GMT 2025
PRIMARY
EPA CompTox
DTXSID40149588
Created by admin on Mon Mar 31 19:58:49 GMT 2025 , Edited by admin on Mon Mar 31 19:58:49 GMT 2025
PRIMARY
WIKIPEDIA
HYDROXYPYRUVIC ACID
Created by admin on Mon Mar 31 19:58:49 GMT 2025 , Edited by admin on Mon Mar 31 19:58:49 GMT 2025
PRIMARY
JECFA MONOGRAPH
456
Created by admin on Mon Mar 31 19:58:49 GMT 2025 , Edited by admin on Mon Mar 31 19:58:49 GMT 2025
PRIMARY
CHEBI
30841
Created by admin on Mon Mar 31 19:58:49 GMT 2025 , Edited by admin on Mon Mar 31 19:58:49 GMT 2025
PRIMARY
DRUG BANK
DB02951
Created by admin on Mon Mar 31 19:58:49 GMT 2025 , Edited by admin on Mon Mar 31 19:58:49 GMT 2025
PRIMARY
PUBCHEM
964
Created by admin on Mon Mar 31 19:58:49 GMT 2025 , Edited by admin on Mon Mar 31 19:58:49 GMT 2025
PRIMARY
MESH
C012375
Created by admin on Mon Mar 31 19:58:49 GMT 2025 , Edited by admin on Mon Mar 31 19:58:49 GMT 2025
PRIMARY