DAZOLICINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C17H24ClN3S
Molecular Weight	337.911
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)N1CCN=C1CN2CCCCSC3=C2C=C(Cl)C=C3

InChI

InChIKey=RZAGBWYFAWQKAE-UHFFFAOYSA-N

InChI=1S/C17H24ClN3S/c1-13(2)21-9-7-19-17(21)12-20-8-3-4-10-22-16-6-5-14(18)11-15(16)20/h5-6,11,13H,3-4,7-10,12H2,1-2H3

HIDE SMILES / InChI

Description
Sources: https://patents.google.com/patent/DE905525 | https://www.ncbi.nlm.nih.gov/pubmed/7194081

Dazolicine is an anti-arrhythmic compound, developed by the German company Roechlingsche Eisen & Stahl. In patients with various types of arrhythmia, after i.v. injection the drug proved to have very strong antiarrhythmic potency and rather a low incidence of side effects. After oral treatment, ectopic beats were eliminated in only 4 of 10 patients.

Originator

Approval Year

PubMed

Title	Date	PubMed
[Anti-arrhythmic effect of dazolicin. Clinical-pharmacological research].	1980	7194081

Patents

Name

Type

Language

DAZOLICINE

Official Name

English

8-CHLORO-3,4,5,6-TETRAHYDRO-6-((1-ISOPROPYL-2-IMIDAZOLIN-2-YL)METHYL)-2H-1,6-BENZOTHIAZOCINE

Systematic Name

English

dazolicine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C47793