U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C20H17ClN2O3
Molecular Weight 368.814
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of KETAZOLAM

SMILES

CN1C2=C(C=C(Cl)C=C2)C3(OC(C)=CC(=O)N3CC1=O)C4=CC=CC=C4

InChI

InChIKey=PWAJCNITSBZRBL-UHFFFAOYSA-N
InChI=1S/C20H17ClN2O3/c1-13-10-18(24)23-12-19(25)22(2)17-9-8-15(21)11-16(17)20(23,26-13)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3

HIDE SMILES / InChI
KETAZOLAM, a benzodiazepine with an additional d-face-fused heterocyclic ring, possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is used for the treatment of anxiety and spasticity.

Approval Year

PubMed

PubMed

TitleDatePubMed
Double-blind placebo-controlled efficacy study of ketazolam (U-28,774).
1976
Ketazolam and diazepam in anxiety: a controlled study.
1980 Oct
Name Type Language
KETAZOLAM
INN   MART.   MI   USAN   WHO-DD  
USAN   INN  
Official Name English
KETAZOLAM [USAN]
Common Name English
UNAKALM
Brand Name English
U-28,774
Code English
U-28774
Code English
ANSIETEN
Brand Name English
ANXON
Brand Name English
(±)-KETAZOLAM
Common Name English
11-CHLORO-8,12B-DIHYDRO-2,8-DIMETHYL-12B-PHENYL-4H-(1,3)OXAZINO(3,2-D)(1,4)BENZODIAZEPINE-4,7(6H)-DIONE
Common Name English
ANSEREN
Brand Name English
Ketazolam [WHO-DD]
Common Name English
4H-(1,3)OXAZINO(3,2-D)(1,4)BENZODIAZEPINE-4,7(6H)-DIONE, 11-CHLORO-8,12B-DIHYDRO-2,8-DIMETHYL-12B-PHENYL-
Systematic Name English
ketazolam [INN]
Common Name English
KETAZOLAM [MI]
Common Name English
KETAZOLAM [MART.]
Common Name English
NSC-338158
Code English
CONTAMEX
Brand Name English
LOFTRAN
Brand Name English
Classification Tree Code System Code
WHO-VATC QN05BA10
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
WHO-ATC N05BA10
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
NCI_THESAURUS C1012
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
DEA NO. 2772
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
Code System Code Type Description
WIKIPEDIA
KETAZOLAM
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
PRIMARY
MESH
C002072
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
PRIMARY
PUBCHEM
33746
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
PRIMARY
CAS
103794-94-1
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
SUPERSEDED
DRUG CENTRAL
1525
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
PRIMARY
EPA CompTox
DTXSID20865350
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
PRIMARY
ECHA (EC/EINECS)
248-346-3
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
PRIMARY
FDA UNII
92A214MD7Y
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
PRIMARY
MERCK INDEX
M6615
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
PRIMARY Merck Index
NSC
338158
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
PRIMARY
RXCUI
28181
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
PRIMARY RxNorm
SMS_ID
100000082849
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
PRIMARY
CAS
27223-35-4
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
PRIMARY
EVMPD
SUB08368MIG
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
PRIMARY
DRUG BANK
DB01587
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
PRIMARY
ChEMBL
CHEMBL2104356
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
PRIMARY
NCI_THESAURUS
C83854
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
PRIMARY
INN
3107
Created by admin on Wed Jul 05 22:51:15 UTC 2023 , Edited by admin on Wed Jul 05 22:51:15 UTC 2023
PRIMARY