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Details

Stereochemistry ABSOLUTE
Molecular Formula C23H27ClO4
Molecular Weight 402.911
Optical Activity UNSPECIFIED
Defined Stereocenters 6 / 6
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DELMADINONE ACETATE

SMILES

[H][C@@]12CC[C@](OC(C)=O)(C(C)=O)[C@@]1(C)CC[C@@]3([H])[C@@]2([H])C=C(Cl)C4=CC(=O)C=C[C@]34C

InChI

InChIKey=CGBCCZZJVKUAMX-DFXBJWIESA-N
InChI=1S/C23H27ClO4/c1-13(25)23(28-14(2)26)10-7-18-16-12-20(24)19-11-15(27)5-8-21(19,3)17(16)6-9-22(18,23)4/h5,8,11-12,16-18H,6-7,9-10H2,1-4H3/t16-,17+,18+,21-,22+,23+/m1/s1

HIDE SMILES / InChI
Delmadinone is a steroid with progestogenic, anti-androgenic and weak glucocorticoid action, synthesized in Syntex S.A. Acetate ester of delmadinone is used in veterinary under tradenames Tardak for cats and dogs for the treatment of excessive or aberrant sexual behaviour, including vagrancy, for the relief of prostatic hypertrophy, circum-anal tumors and for the treatment of certain forms of aggressiveness, nervousness, epileptiform seizures and corticosteroid-resistant pruritus. Delmadinone acetate blocks androgen receptors inhibit 5-reductase, which catalyzes the transformation of testosterone to the more potent androgen 5-dihydrotestosterone and decreases the production of testosterone by inhibiting gonadotropin release.

Approval Year

PubMed

PubMed

TitleDatePubMed
[Treatment of fibroepithelial hyperplasia (FEH) of the mammary gland in the cat with the progesterone antagonist Aglépristone (Alizine)].
2003 Mar
Efficacies of osaterone and delmadinone in the treatment of benign prostatic hyperplasia in dogs.
2008 Aug 9
Name Type Language
DELMADINONE ACETATE
MART.   MI   USAN  
USAN  
Official Name English
CYPROTERONE ACETATE IMPURITY I [EP IMPURITY]
Common Name English
DELMADINONE ACETATE [MI]
Common Name English
DELMADINONE ACETATE [USAN]
Common Name English
RS-1301
Code English
PREGNA-1,4,6-TRIENE-3,20-DIONE, 17-(ACETYLOXY)-6-CHLORO-
Systematic Name English
6-Chloro-3,20-dioxopregna-1,4,6-trien-17-yl acetate
Systematic Name English
6-Chloro-17-hydroxypregna-1,4,6-triene-3,20-dione acetate
Common Name English
DELMADINONE ACETATE [MART.]
Common Name English
Code System Code Type Description
ChEMBL
CHEMBL2104598
Created by admin on Fri Dec 15 15:22:56 GMT 2023 , Edited by admin on Fri Dec 15 15:22:56 GMT 2023
PRIMARY
NCI_THESAURUS
C171686
Created by admin on Fri Dec 15 15:22:56 GMT 2023 , Edited by admin on Fri Dec 15 15:22:56 GMT 2023
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FDA UNII
92833M0LD9
Created by admin on Fri Dec 15 15:22:56 GMT 2023 , Edited by admin on Fri Dec 15 15:22:56 GMT 2023
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DRUG CENTRAL
3130
Created by admin on Fri Dec 15 15:22:56 GMT 2023 , Edited by admin on Fri Dec 15 15:22:56 GMT 2023
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WIKIPEDIA
Delmadinone acetate
Created by admin on Fri Dec 15 15:22:56 GMT 2023 , Edited by admin on Fri Dec 15 15:22:56 GMT 2023
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MERCK INDEX
m4153
Created by admin on Fri Dec 15 15:22:56 GMT 2023 , Edited by admin on Fri Dec 15 15:22:56 GMT 2023
PRIMARY Merck Index
PUBCHEM
10135765
Created by admin on Fri Dec 15 15:22:56 GMT 2023 , Edited by admin on Fri Dec 15 15:22:56 GMT 2023
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CAS
13698-49-2
Created by admin on Fri Dec 15 15:22:56 GMT 2023 , Edited by admin on Fri Dec 15 15:22:56 GMT 2023
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ECHA (EC/EINECS)
237-219-8
Created by admin on Fri Dec 15 15:22:56 GMT 2023 , Edited by admin on Fri Dec 15 15:22:56 GMT 2023
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EPA CompTox
DTXSID60160018
Created by admin on Fri Dec 15 15:22:56 GMT 2023 , Edited by admin on Fri Dec 15 15:22:56 GMT 2023
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SMS_ID
300000023725
Created by admin on Fri Dec 15 15:22:56 GMT 2023 , Edited by admin on Fri Dec 15 15:22:56 GMT 2023
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