U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C20H25NO2
Molecular Weight 311.418
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of KETORFANOL

SMILES

[H][C@]12CC3=C(C(O)=CC=C3)[C@@]5(CCN1CC4CC4)CC(=O)CC[C@@]25[H]

InChI

InChIKey=ORMBBVGVPWUEMQ-QKLQHJQFSA-N
InChI=1S/C20H25NO2/c22-15-6-7-16-17-10-14-2-1-3-18(23)19(14)20(16,11-15)8-9-21(17)12-13-4-5-13/h1-3,13,16-17,23H,4-12H2/t16-,17+,20-/m0/s1

HIDE SMILES / InChI

Description

KETORFANOL, a morphinan derivative, is an opioid analgesic. It showed potent antiwrithing activity in the animal assay. It was equipotent with morphine as an agonist and lacked antagonist activity up to 10 mg/kg.

Originator

Manmade A., et al.
1

Approval Year

Unknown
139,594

PubMed

ACTIVE MOIETY
Structure of KETORFANOL
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966