KETORFANOL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H25NO2
Molecular Weight	311.418
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of KETORFANOL

Structure Search

SMILES

OC1=C2C(C[C@@H]3[C@@H]4CCC(=O)C[C@]24CCN3CC5CC5)=CC=C1

InChI

InChIKey=ORMBBVGVPWUEMQ-QKLQHJQFSA-N

InChI=1S/C20H25NO2/c22-15-6-7-16-17-10-14-2-1-3-18(23)19(14)20(16,11-15)8-9-21(17)12-13-4-5-13/h1-3,13,16-17,23H,4-12H2/t16-,17+,20-/m0/s1

HIDE SMILES / InChI

Description
Sources: https://www.genome.jp/dbget-bin/www_bget?dr:D04653 | https://www.ncbi.nlm.nih.gov/pubmed/7310820

KETORFANOL, a morphinan derivative, is an opioid analgesic. It showed potent antiwrithing activity in the animal assay. It was equipotent with morphine as an agonist and lacked antagonist activity up to 10 mg/kg.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
(-)-4-Hydroxymorphinanones: their synthesis and analgesic activity.	1981-12	7310820

Name

Type

Language

SBW-22

Preferred Name

English

KETORFANOL

Official Name

English

ketorfanol [INN]

Common Name

English

KETORFANOL [USAN]

Common Name

English

MORPHINAN-6-ONE, 17-(CYCLOPROPYLMETHYL)-4-HYDROXY-

Systematic Name

English

17-(Cyclopropylmethyl)-4-hydroxymorphinan-6-one

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1506

Created by admin on Wed Apr 02 08:52:02 GMT 2025 , Edited by admin on Wed Apr 02 08:52:02 GMT 2025

Code System Code Type Description

CAS

79798-39-3

Created by admin on Wed Apr 02 08:52:02 GMT 2025 , Edited by admin on Wed Apr 02 08:52:02 GMT 2025

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WIKIPEDIA

Ketorfanol

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INN

5308

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ChEMBL

CHEMBL2104366

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PUBCHEM

5490677

Created by admin on Wed Apr 02 08:52:02 GMT 2025 , Edited by admin on Wed Apr 02 08:52:02 GMT 2025

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NCI_THESAURUS

C66000

Created by admin on Wed Apr 02 08:52:02 GMT 2025 , Edited by admin on Wed Apr 02 08:52:02 GMT 2025

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USAN

T-95

Created by admin on Wed Apr 02 08:52:02 GMT 2025 , Edited by admin on Wed Apr 02 08:52:02 GMT 2025

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FDA UNII

8Z0ZXE70XL

Created by admin on Wed Apr 02 08:52:02 GMT 2025 , Edited by admin on Wed Apr 02 08:52:02 GMT 2025

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SMS_ID

100000083077

Created by admin on Wed Apr 02 08:52:02 GMT 2025 , Edited by admin on Wed Apr 02 08:52:02 GMT 2025

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EPA CompTox

DTXSID60868547

Created by admin on Wed Apr 02 08:52:02 GMT 2025 , Edited by admin on Wed Apr 02 08:52:02 GMT 2025

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EVMPD

SUB08375MIG

Created by admin on Wed Apr 02 08:52:02 GMT 2025 , Edited by admin on Wed Apr 02 08:52:02 GMT 2025

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ACTIVE MOIETY


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