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Details

Stereochemistry ACHIRAL
Molecular Formula C23H23N5O5
Molecular Weight 449.4592
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CH-1504

SMILES

NC1=NC(N)=C2C=C(CCC3=CC=C(C=C3)C(=O)NC(CC(=C)C(O)=O)C(O)=O)C=CC2=N1

InChI

InChIKey=NAWXUBYGYWOOIX-UHFFFAOYSA-N
InChI=1S/C23H23N5O5/c1-12(21(30)31)10-18(22(32)33)26-20(29)15-7-4-13(5-8-15)2-3-14-6-9-17-16(11-14)19(24)28-23(25)27-17/h4-9,11,18H,1-3,10H2,(H,26,29)(H,30,31)(H,32,33)(H4,24,25,27,28)

HIDE SMILES / InChI

Approval Year

Name Type Language
CH-1504
Common Name English
AA-243
Code English
M-TREX
Common Name English
MOBILETREX
Common Name English
CH 1504
Code English
TRIDAM
Common Name English
2-((4-(2-(2,4-DIAMINOQUINAZOLIN-6-YL)ETHYL)BENZOYL)AMINO)-4-METHYLENE-PENTANEDIOIC ACID
Systematic Name English
GLUTAMIC ACID, N-(4-(2-(2,4-DIAMINO-6-QUINAZOLINYL)ETHYL)BENZOYL)-4-METHYLENE-
Systematic Name English
Code System Code Type Description
FDA UNII
8Y3RH62XPB
Created by admin on Sat Dec 16 12:12:56 GMT 2023 , Edited by admin on Sat Dec 16 12:12:56 GMT 2023
PRIMARY
CAS
238074-89-0
Created by admin on Sat Dec 16 12:12:56 GMT 2023 , Edited by admin on Sat Dec 16 12:12:56 GMT 2023
PRIMARY
CLINICAL_TRIALS.GOV
CH-1504
Created by admin on Sat Dec 16 12:12:56 GMT 2023 , Edited by admin on Sat Dec 16 12:12:56 GMT 2023
PRIMARY Official Title: A Phase II, Multi-center, Randomized, Double-blind, Methotrexate Controlled Study to Assess the Clinical Efficacy, Safety, and Tolerability of CH-1504 in Subjects With Active Rheumatoid ArthritisPurpose: The purpose of this trial is to assess the clinical effect of CH-1504 at doses of 0.25, 0.5 and 1.0 mg per day in patients with active rheumatoid arthritis by determining the proportion of patients achieving an American College of Rheumatology (ACR) 20% improvement response.
PUBCHEM
9846537
Created by admin on Sat Dec 16 12:12:56 GMT 2023 , Edited by admin on Sat Dec 16 12:12:56 GMT 2023
PRIMARY