Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C5H7N3O2.CH4O3S |
| Molecular Weight | 237.234 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CS(O)(=O)=O.CN1C(C)=NC=C1[N+]([O-])=O
InChI
InChIKey=FKWSWLFYXRLGRR-UHFFFAOYSA-N
InChI=1S/C5H7N3O2.CH4O3S/c1-4-6-3-5(7(4)2)8(9)10;1-5(2,3)4/h3H,1-2H3;1H3,(H,2,3,4)
Dimetridazole is an anti-fungal and anti-protozoal drug traditionally used in veterinary for the prevention and treatment of histomoniasis in turkeys, genital trichomoniasis in cattle and hemorrhagic enteritis in pigs. Results from the in vitro and in vivo tests suggested, that dimetridazole was not genotoxic compound, but its use is legally limited, although this compound is still can be found in eggs.
Approval Year
Sample Use Guides
in veterinary: After laying hens had been dosed orally with dimetridazole (DMZ) for 3 days (50 and 250 mg/kg body weight (b.w.)) or intramuscularly, also for 3 days (50 mg/kg b.w.), the residues were determined in serum, liver, breast and thigh muscle by liquid chromatography.
Route of Administration:
Other
The in vitro susceptibility of four Trichomonas gallinae isolates to five nitroimidazolic drugs, that is, carnidazole, dimetridazole, metronidazole, ornidazole and ronidazole, was also determined. Minimal lethal concentrations (MLCs) of these drugs were obtained. For carnidazole, dimetridazole, metronidazole and ornidazole the MLC ranged between 93.75-500 microg ml.
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93856-85-0
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DTXSID40917486
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8WI17L7FIJ
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16205819
Created by
admin on Sat Dec 16 05:50:36 GMT 2023 , Edited by admin on Sat Dec 16 05:50:36 GMT 2023
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299-119-0
Created by
admin on Sat Dec 16 05:50:36 GMT 2023 , Edited by admin on Sat Dec 16 05:50:36 GMT 2023
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ACTIVE MOIETY
SUBSTANCE RECORD
