U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C20H34O6
Molecular Weight 370.4804
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of 6-KETOPROSTAGLANDIN F1.ALPHA.

SMILES

CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC(=O)CCCCC(O)=O

InChI

InChIKey=KFGOFTHODYBSGM-ZUNNJUQCSA-N
InChI=1S/C20H34O6/c1-2-3-4-7-14(21)10-11-16-17(19(24)13-18(16)23)12-15(22)8-5-6-9-20(25)26/h10-11,14,16-19,21,23-24H,2-9,12-13H2,1H3,(H,25,26)/b11-10+/t14-,16+,17+,18+,19-/m0/s1

HIDE SMILES / InChI
6-Ketoprostaglandin F1alpha (6-keto PGF1a) is a stable hydrolysis product of prostacyclin (PGI2). Due to the short half-life of PGI2, the production of prostacyclin is typically monitored by measurement of the 6-keto-PGF1a metabolite. 6-keto prostaglandin F1α is measured in patients with chronic pulmonary heart disease, where its level was significantly lowered compared with normal controls.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Production of 6-keto-prostaglandin F1 alpha by rat granulosa cells in vitro.
1982 Nov
Decreased in vitro production of 6-keto-prostaglandin F1 alpha by uterine arteries from postmenopausal women.
1989 Dec

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
6-KETOPROSTAGLANDIN F1.ALPHA.
Common Name English
6-KETO-PGF1.ALPHA.
Common Name English
PROST-13-EN-1-OIC ACID, 9,11,15-TRIHYDROXY-6-OXO-, (9.ALPHA.,11.ALPHA.,13E,15S)-
Systematic Name English
EPOPROSTENOL RELATED COMPOUND A [USP-RS]
Common Name English
EPOPROSTENOL RELATED COMPOUND A
USP-RS  
Common Name English
6-OXOPROSTAGLANDIN F1ALPHA
Common Name English
6-OXO-PGF1.ALPHA.
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID001317937
Created by admin on Sat Dec 16 08:09:43 GMT 2023 , Edited by admin on Sat Dec 16 08:09:43 GMT 2023
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RS_ITEM_NUM
1237611
Created by admin on Sat Dec 16 08:09:43 GMT 2023 , Edited by admin on Sat Dec 16 08:09:43 GMT 2023
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FDA UNII
8URB805JJJ
Created by admin on Sat Dec 16 08:09:43 GMT 2023 , Edited by admin on Sat Dec 16 08:09:43 GMT 2023
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CAS
58962-34-8
Created by admin on Sat Dec 16 08:09:43 GMT 2023 , Edited by admin on Sat Dec 16 08:09:43 GMT 2023
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CHEBI
28158
Created by admin on Sat Dec 16 08:09:43 GMT 2023 , Edited by admin on Sat Dec 16 08:09:43 GMT 2023
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PUBCHEM
5280888
Created by admin on Sat Dec 16 08:09:43 GMT 2023 , Edited by admin on Sat Dec 16 08:09:43 GMT 2023
PRIMARY